N. Wang

This paper develops an efficient gene excision system in maize using inducible recombinases to improve transformation and regeneration of fertile plants.

The paper identifies broadly neutralizing antibodies against SARS-CoV-2 and related sarbecoviruses, highlighting a conserved epitope on the spike protein as a potential vaccine target.

A purified inactivated SARS-CoV-2 vaccine candidate (PiCoVacc) induces neutralizing antibodies in animals and shows safety and partial to complete protection against SARS-CoV-2 strains.

The paper uses proteomics to study citrus vascular responses to HLB, finding increased peroxidases and serine proteases during infection.

The paper determines the cryo-EM structure of the 2019-nCoV Spike protein in the prefusion conformation and shows higher ACE2 binding affinity compared to SARS-CoV.

This study identifies a non-hypermucoviscous ST11 hypervirulent K. pneumoniae strain lacking classical virulence factors, showing increased virulence through ampR and WcaJ mechanisms.

The paper investigates the genetic basis of rumen evolution by comparing transcriptomes and genomic data across ruminants, camels, and cetaceans, identifying key genetic innovations.

This study identifies four clinically used drugs with high binding capacity to SARS-CoV main protease, a potential target for treating 2019-nCoV infection.

The paper introduces an efficient long fragment editing technique for scarless genome engineering in E. coli, enabling large-scale DNA insertion and deletion with high success rates.

This study develops a reversed paired-gRNA plasmid cloning strategy to eliminate plasmid instability caused by direct repeats, achieving efficient genome editing in E. coli.

The paper identifies CbuSPL9 and its interacting protein CbuHMGA in Catalpa bungei, showing they form a heterodimer and may regulate flowering development, not transition.

This study identifies ALBA proteins in Arabidopsis as redundant regulators of growth and flowering, with minimal impact on transcriptome composition.

This study shows that loss of the ATRX/DAXX complex disrupts rDNA heterochromatinization, leading to increased rDNA transcription and promoting glioma development.

This paper introduces AbMap, a high-throughput epitope mapping technology that identifies epitopes for over 200 antibodies in a single run, including 14 anti-PD-1 antibodies.

This study examines the impact of simulated acid rain on soil respiration and microbial communities in a Moso bamboo forest, finding no significant effect on respiration rates but a notable impact on bacterial diversity.

This study examines the assembly properties of SyFtsZ from Synechocystis sp. PCC 6803, identifying different protofilament structures formed in GTP and GDP conditions.

This study identifies new ATCase inhibitors by targeting a previously unknown regulatory region and active site, showing strong anticancer effects in cell lines and xenograft models.

This paper identifies five fluorescent proteins suitable for high-resolution live imaging in rice leaves and introduces a method for transient transformation.

The paper identifies a monophyletic Arthrobacter cluster adapted to cold environments and shows that specific genomic changes correlate with cold tolerance.

The paper reveals the structure of the chloroplast chaperonin system using Cryo-EM, showing its hetero-oligomeric composition and functional properties.

This study reconstructs the phylogeny of Portulacineae and examines molecular evolution correlates with adaptation to harsh environments, identifying gene duplications and expansions linked to stress responses.

This study identifies that Salmonella effectors SseK1 and SseK3 glycosylate death domain proteins in TNF and TRAIL signaling pathways, modulating their function during infection.

The paper introduces an open-source software tool for automated tracking of biopolymer networks in 2D and 3D using stretching open active contours, demonstrating its application in live cell studies.

This study uses cryo-EM to show that ACE2 binding and trypsin cleavage of SARS-CoV spike protein do not cause major conformational changes or expose the S2 cleavage site.

This study uses single molecule FRET to show Cas9 undergoes conformational changes and long-range allosteric communication that regulate DNA cleavage, identifying key residues for improving CRISPR/Cas9 specificity.

The paper analyzes concordance and conflict in avian phylogenies over time, finding persistent conflicts in major clades despite advances in phylogenetic methods.