S. Khan

The paper identifies an extended COPI binding motif in the SARS-CoV-2 spike protein that modulates its interaction with COPI subunits and is critical for retrograde trafficking.

This study shows oral glucosamine improves neurological symptoms in a mouse model with misfolded HGSNAT due to a Pro304Leu mutation.

This study uses single-cell RNA-sequencing to characterize human dura and meningioma, revealing distinct immune microenvironments and TCR overlap between matched samples.

The paper compares antibody reactivity patterns between natural SARS-CoV-2 infection and mRNA vaccination, finding that vaccination induces stronger and broader antibody responses, including cross-reactivity against SARS antigens.

This study shows that SARS-CoV-2 spike protein induces inflammation in macrophages and epithelial cells via TLR2-dependent NF-κB activation, suggesting TLR2 as a therapeutic target for COVID-19.

This paper describes the development of a novel adenoviral vector, HAdV-20-42-42, which shows promise for gene therapy and vaccination due to its low seroprevalence and effective transduction capabilities.

The paper shows that population density affects competition outcomes between Gardnerella subgroup D and C isolates from the human vaginal microbiome.

This paper identifies uromodulin (THP) as a protective factor in sepsis, showing its role in enhancing mononuclear phagocyte function and reducing mortality in mice.

This study develops a low-cost method to create 3D-printed tissue scaffolds from plant-derived cellulose, aiming to mimic blood vessel structures for tissue engineering.

This study develops a 3D tissueoids model using the AXTEX-4D platform to better simulate tumor microenvironment and drug resistance compared to 2D and collagen-based 3D systems.

The paper shows lipid exposure alters gene expression and chromatin features in mammary cells, linking these changes to ER-negative breast cancer development.

This paper demonstrates high-resolution imaging of FDG uptake in a 3D tumor-stroma model using radioluminescence microscopy, showing significant FDG uptake in both tumor and stromal compartments.

The paper introduces AXTEX-4D, a 3D ex vivo platform for testing immunotherapy drugs by mimicking the tumor microenvironment to assess immune cell responses and drug efficacy.

This study uses a coronavirus antigen microarray to identify distinct antibody reactivity patterns in SARS-CoV-2 convalescent plasma, showing high concordance with existing assays and revealing clusters with potential implications for treatment efficacy.

This study identifies CIP2A as a subtype-specific driver of DNA damage-induced basal-like breast cancer, showing its role in checkpoint signaling and therapeutic vulnerability.

The paper shows that subgroup D of Gardnerella spp. persists in the vaginal microbiome due to a generalist lifestyle and negative-frequency dependent selection.

This paper develops a high-resolution microscopy method to image FDG in tumor organoids, mirroring clinical PET scans and predicting treatment response.

This study evaluates how sunlight affects the efficacy of streptomycin and oxytetracycline against Gram-negative and Gram-positive bacteria over 7-14 days.

This study investigates the biodegradation of polyester polyurethane by Aspergillus flavus G10 using multiple analytical techniques and identifies conditions that enhance degradation.

The paper introduces a low-cost, portable imaging system for specific COVID-19 antibody testing using microarrays, achieving performance comparable to expensive commercial readers.

This paper validates a coronavirus antigen microarray to distinguish SARS-CoV-2 convalescent blood from pre-pandemic controls, showing improved discrimination with spike and nucleoprotein antigens.

This study identifies mutations in the helicase domain of Rqh1 as critical for its role in the DNA replication checkpoint in fission yeast, with implications for human cancer predisposition syndromes.

The paper develops a coronavirus antigen microarray to study serologic cross-reactivity between common human coronaviruses and SARS-CoV-2, finding high IgG reactivity to common coronaviruses and low reactivity to SARS-CoV-2 with some cross-reactivity to conserved antigens.

This study develops a multi-epitope subunit vaccine against Norovirus using computational vaccinology, selecting antigenic epitopes and modeling the vaccine structure for potential experimental validation.

This study evaluates the mutagenic effectiveness and efficiency of gamma rays and sodium azide in cowpea to establish an optimal mutagenesis protocol for genetic improvement.

This study identifies a novel HIF-1α-αMβ2 integrin-NETosis axis in fibrotic interstitial lung disease, showing hypoxia enhances NETosis and integrin expression.

This study examines factors affecting the detection of GM rice, showing that husk presence, DNA extraction methods, and PCR primers significantly influence detection outcomes.

The paper examines the role of PIP2-type aquaporins in photosynthesis under varying humidity conditions, finding that AtPIP2;4 enhances stomatal conductance under low humidity, while AtPIP2;5 affects mesophyll conductance.

This study shows that Dillenia indica fruit extract lowers fasting glucose and cholesterol levels in diabetic and hyperlipidemic rats without liver or kidney toxicity.

The paper investigates interactions among Gardnerella subgroups in vitro, finding competition reduces growth rates of subgroups A, B, and C while increasing subgroup D's growth.