T. Yamamoto

The paper theoretically studies chromatin dynamics driven by loop extrusion to show that longer linker DNA increases promoter contact probability with transcriptional condensates when loop extrusion is active.

This study investigates how cell cycle-dependent active stress influences epithelial remodeling by analyzing cell shape and dynamics in model monolayers.

The paper shows miRNAs slow translating ribosomes to prevent protein misfolding without significantly affecting protein abundance.

This study models chromatin phase separation in a chromatin brush system, showing that it occurs when the brush height drops below a threshold due to anti-correlation between activators and silencers.

The paper models paraspeckles as triblock copolymer micelles and predicts structural changes based on arcRNA block length, validated by experiments.

This study identifies miRNAs other than miR-122 that support HCV replication in non-hepatic cells by interacting with the viral 5UTR and stabilizing the IRES structure.

The paper shows diploid male gametes bypass hybrid sterility in rice hybrids by avoiding allelic conflicts at hybrid sterility loci through meiotic anomalies.

This paper generates human bronchial organoids that support SARS-CoV-2 infection and drug testing, showing reduced viral load with TMPRSS2 inhibition.

This study constructs a live-attenuated SHIV expressing Ag85B and shows it induces strong sterile immunity against pathogenic SHIV in macaques.

This study investigates recent trends and risk factors of sleep-related sudden infant deaths in Japan, identifying high odds ratios for teenage mothers and later birth order.

The paper investigates how adherens junctions generate cryptic lamellipodia in epithelial cells, enabling collective migration by recruiting actin regulators and facilitating follower cell trailing.

This paper introduces a method to determine the double bond position in unsaturated fatty acids using LC-MS with solvent plasmatization and CID fragmentation.

This study modifies a Bayesian framework to reconstruct foot-and-mouth disease transmission networks by incorporating farm-level covariates, showing improved accuracy and insights into outbreak dynamics.

This study identifies and characterizes two gene clusters in Paraburkholderia sp. strain KU-46 involved in DNP catabolism, revealing a unique pathway for DNP degradation via 4-nitrophenol.

The paper evaluates a quantitative malaria diagnostic system using a fluorescent Blue-ray optical device in Kenya, showing higher sensitivity and specificity than RDT.

This study identifies miR-26a as a regulator of extracellular vesicle secretion in prostate cancer cells by targeting SHC4, PFDN4, and CHORDC1, which inhibits tumor progression.

This study compares microbiome composition in oral and atherosclerotic plaque samples from patients with and without periodontitis, finding no direct link between oral bacteria and atheromatous plaque formation.

The paper shows that centrosome duplication cycle incompatibility with DNA replication causes instability in non-diploid mammalian somatic cells.