W. Xing

Quantitative reconstitution of yeast RNA processing bodies

This study reconstitutes yeast RNA processing bodies from purified components, showing that their composition and dynamics can be recapitulated quantitatively.

Skeletal muscle lineage is dispensable for appendage regeneration in axolotl

This study shows that skeletal muscle is not required for limb regeneration in axolotls, as Pax7 mutants regenerate limbs with normal patterns and cell composition.

Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton

This study shows that TFR1-mediated iron uptake in osteoclasts affects mitochondrial function and cytoskeleton, leading to increased bone mass in female mice.

WWP1 deficiency protects from cardiac remodeling induced by simulated microgravity

This study shows that WWP1 deficiency protects against cardiac remodeling and function decline caused by simulated microgravity in mice.

Antagonistic modules, SIB1 and LSD1, regulate photosynthesis-associated nuclear genes via GOLDEN2-LIKE transcription factors in Arabidopsis

This study shows SIB1 and LSD1 antagonistically regulate GLK1/2 to control PhANGs expression, affecting chloroplast biogenesis and 1O2 homeostasis in Arabidopsis.

Phytophthora sojae effector Avr1d functions as E2 competitor and inhibits ubiquitination activity of GmPUB13 to facilitate infection

This study identifies Avr1d as a Phytophthora sojae effector that inhibits GmPUB13 E3 ligase activity by competing with E2 ubiquitin conjugating enzymes, stabilizing the susceptibility factor and facilitating infection.

A quantitative inventory of yeast P body proteins reveals principles of compositional and specificity

The paper quantifies yeast P body protein concentrations, finding only 7 proteins are highly concentrated, while others are lower, and shows sequence elements drive Dcp2 localization.

A plant receptor-like kinase promotes cell-to-cell spread of RNAi and is targeted by a virus

The paper identifies BAM1 as a positive regulator of RNAi cell-to-cell spread and shows that a viral protein inhibits this process by interacting with BAM1 and BAM2.