Y. Gao

This study evaluates the effectiveness of a disinfectant combining highly complexed iodine and compound organic acids in inactivating African swine fever virus under various conditions, showing dose- and time-dependent inactivation with synergistic effects.

This study analyzes the impact of socio-economic factors on surface water quality at provincial boundaries in China, identifying key factors affecting water quality.

This paper develops a lightweight deep learning model to automatically identify chicken distress calls, achieving high accuracy with reduced computational requirements.

This paper compares nine membrane materials for passive eDNA collection in marine environments, finding that five minutes of submersion yields comparable results to conventional filtering.

This study shows that humanized mice can be infected by SARS-CoV-2, leading to immune responses and immunopathology, providing a model for studying the virus and testing therapies.

The paper develops a machine learning tool called Helcaraxe to detect ice artefacts in processed macromolecular diffraction data, achieving better performance than previous methods.

This study determines the cryo-EM structure of VAR2CSA and its complex with CSA, revealing conformational changes and identifying mutations that abolish CSA binding and cytoadherence to placental and tumor cells.

The paper develops a population model to analyze optimal reproductive strategies in incipient multicellular organisms, finding that organism size and cellular interaction influence reproductive success.

The paper develops RasperGade16S to model 16S rRNA gene copy number uncertainty, showing it improves GCN prediction and supports correction in most microbial communities.

This study identifies SIRT5 as a desuccinylase that regulates LDHA succinylation, promoting prostate cancer metastasis and progression.

This study shows ASH1L's enzymatic activity is essential for MLL-AF9-induced leukemogenesis by enhancing target gene expression through histone modification.

The paper identifies GPS2 as an inhibitor of Mul1-mediated ubiquitination that regulates mitochondria-associated translation by targeting RNA-binding and translation factors.

The paper investigates how herbivory and nutrient availability fluctuations interact to affect alien plant dominance in synthetic communities.

The paper determines the structure of infective Getah virus at 2.8 Å resolution using cryo-EM, revealing glycosylation, S-acylation sites, and lipid interactions critical for immune evasion and host cell invasion.

The paper uses single-cell sequencing to analyze glioma-associated microglia and macrophages, revealing their distinct roles in tumor progression and clinical outcomes.

The study tracks IgG antibody levels against SARS-CoV-2 RBD in convalescent plasma donors over 12 months, showing sustained positivity and gender/age-related differences.

This study shows TMEM120A does not mediate poking- or stretch-induced currents and identifies a specific coenzyme A-binding site through cryo-EM structures.

This study shows PLK2 loss predicts better response to PLK1 inhibitors in triple-negative breast cancer and suggests PLK2 as a biomarker for treatment response.

The paper reports the structures of M. tuberculosis cytochrome bcc complexed with two anti-TB drugs, revealing binding sites and interactions that inform inhibitor design.

This study identifies SiAUX1 as critical for lateral root development in Setaria italica, revealing its role in cell volume distribution and vascular strand formation through mutant analysis and RNAseq.

This study identifies changes in the urinary proteome of rats undergoing regular swimming exercise, showing distinct protein differences linked to glucose metabolism and immunity.

This study develops an IFN-armed RBD dimer vaccine that induces strong neutralizing antibodies and T cell responses, offering complete protection against SARS-CoV-2 in rhesus macaques with a single dose.

This study uses multi-omics profiling to analyze U2AF1 mutations in myeloid malignancies, revealing altered RNA binding, splicing, and stress granule formation.

This study identifies three ultrapotent SARS-CoV-2 neutralizing antibodies effective against B.1.351 variants, showing synergistic effects and protective efficacy in mice.

The paper analyzes microbial genomic trait evolution and finds that pulsed evolution is prevalent and predominant, with two distinct types of pulses detected.

This study identifies renalase (RNLS) as a biomarker in pancreatic ductal adenocarcinoma (PDAC), showing elevated tissue and plasma levels correlate with worse tumor characteristics and reduced survival.

Overexpression of VDAL in Arabidopsis enhances resistance to Verticillium dahliae by preventing degradation of the transcription factor MYB6 through interaction with PUB25/26 E3 ligases.

This study identifies a non-canonical role of RNF168 at DNA replication forks, showing it suppresses 53BP1 signaling through PCNA binding, independent of its canonical DSB response function.