Z. He

This study identifies distinct CD8+ T cell subsets in non-lymphoid tissues during infection and cancer, revealing their functional roles and regulatory mechanisms.

The paper uses single-cell RNA sequencing to study CD8+ T cell differentiation during infection, revealing molecular determinants and functional heterogeneity in tissue-resident memory cells.

This study shows that combining cold atmospheric plasma with silver nanoparticles significantly increases cytotoxicity in glioblastoma cells through enhanced nanoparticle uptake and oxidative stress.

This study shows that microbial adaptation reduces soil carbon loss under long-term warming by decreasing temperature sensitivity of respiration.

This study presents cryo-EM structures of pannexin 1 from Xenopus tropicalis and Homo sapiens, revealing its heptameric architecture and molecular sieve mechanism for ATP release.

This study shows that Coxiella burnetii phase II can grow under normoxic conditions in ACCM-2 with tryptophan, and its transformant grows robustly without tryptophan, suggesting tryptophan and a temperature-sensitive signal are involved in normoxic growth.

This study shows that CHL1 overexpression reverses chemoresistance to cisplatin and paclitaxel in lung cancer by inhibiting the Akt pathway.

This study uses single-cell RNA sequencing to analyze the cellular diversity and molecular markers in the retina of a trisomy 21 fetus, revealing communication networks and novel markers.

This study investigates how hyperthermia induces neural stem cell differentiation and shows that HSP90 regulates this process through the HIF-1 pathway.

The paper develops a one-step protocol to express EGFP in S. aureus clinical strains for studying adhesion and internalization in epithelial cells, showing high expression efficiency and similar behavior to wild-type strains.

The paper shows that positive selection drives amino acid substitutions with large chemical property changes, while negative selection favors smaller changes, suggesting distinct evolutionary mechanisms.

This paper identifies Spc105 as a new LaeA interaction partner in Aspergillus flavus, showing its role in development, secondary metabolism, and regulatory interdependence with LaeA.

This study identifies FAM83D as a scaffold that recruits CK1α to the mitotic spindle, ensuring proper spindle positioning and timely cell division.

This study identifies USP15 as a host factor for HCV propagation, showing it regulates viral RNA translation and lipid droplet formation in hepatic cells.

This study identifies Cyclin B3's specific role in facilitating metaphase-to-anaphase transition in mouse oocyte meiosis I, while showing it is not required for oocyte maturation or sister chromosome segregation.

This study shows that high IQGAP3 expression in breast cancer is linked to poor prognosis and resistance to radiation therapy.

This study shows that deleting the ycgN gene in B. licheniformis increases gamma-PGA synthesis by raising intracellular ROS levels through P5C accumulation.

The paper investigates speciation mechanisms in mangroves, finding that cycles of isolation and gene flow (MIM) drive speciation between oceanic regions, challenging the traditional model of strict allopatry.

This study shows that IL-33 regulates gene expression in intestinal epithelial cells through its extracellular form, not its nuclear form, by using transgenic mice and ST2-deficient mice.

This study shows that diet modifies the microbiota and CD4+ T cell repertoire in a mouse model of IL-23-induced colitis, leading to disease flares.