Z. Liu

This study shows ANGPTL4 promotes epidermal stem cell proliferation and migration, enhancing wound re-epithelialization in mice.

The paper shows Foxp3 is essential for establishing Treg-specific 3D chromatin architecture during differentiation, though not dependent on a specific dimer formation.

The paper measures antibiotic accumulation in phagosomes of live macrophages infected with Staphylococcus aureus to assess permeability differences between extracellular and intracellular environments.

This study uses a reaction-diffusion model to show that co-factors like IP6 delay Gag lattice assembly, preventing kinetic trapping and enabling productive lattice formation.

This study identifies microbial single nucleotide variants (SNVs) as superior biomarkers for early detection of colorectal cancer, outperforming species-level signatures in multiple validation cohorts.

This study shows FTO stabilizes LINK-A, promoting ESCC progression through MCM3-mediated cell cycle progression and HIF-1α activation.

This study reports the cryo-EM structure of the TOC-TIC supercomplex from Chlamydomonas reinhardtii, revealing its architecture and potential preprotein translocation pathways.

This study uses single-cell RNA sequencing to identify novel subtypes and intratumoral heterogeneity in olfactory neuroblastoma.

This study examines how plant selection and ecological microhabitats influence the microbiomes of revegetated shrubs, finding that microhabitats, not plant species, primarily drive microbial community composition.

This study identifies anthracyclines as potential SARS-CoV-2 inhibitors through a microbial metabolite screening effort, showing they inhibit viral infection via different mechanisms.

This study uses phylogenomic analysis of macaque genomes to show that incomplete lineage sorting and ancient hybridization contributed to the radiation of macaques.

This study identifies VHL mutation as a driver of CE accumulation in ccRCC through the PI3K/AKT pathway, showing that inhibiting cholesterol esterification suppresses tumor aggressiveness.

This study shows that reactivation of human endogenous retroviruses during aging promotes cellular senescence and tissue degeneration, and that blocking this reactivation can alleviate aging.

The paper uses metagenomics to identify 22 RNA viruses in ticks from northeastern China, revealing novel species and highlighting public health risks from emerging tick-borne viruses.

This paper develops cholesterol-deficient T cell membrane-coated nanoparticles to deliver STING agonists for tumor immunotherapy, showing improved blood clearance evasion and enhanced antitumor effects.

This study shows 5-ALA labeling is not specific to transformed glioma cells but can label untransformed cells directly or via PpIX from surrounding tumor cells.

This study determines the structure of the Na+-driven bacterial flagellar stator unit PomAB, revealing mechanisms of ion selectivity, rotor coupling, and stator unit activation.

This study uses a computational model to show that ventricular systolic function affects thrombus formation after EVAR, with specific correlations identified.

This paper develops an mRNA vaccine for chronic hepatitis B that shows strong immunogenicity and persistent virological suppression in mouse models.

This paper reports the structure and function of the photosystem I supercomplex in Ostreococcus tauri, showing it assembles with light-harvesting complexes and exhibits reversible photoacclimation.

This paper clusters and classifies patients with organ failure using ICD codes and graph attention networks, identifying two disease severity-related clusters.

This study identifies a novel catecholaminergic cardiomyocyte population expressing Dbh that contributes to the murine cardiac conduction system through transcriptomic, genetic, and optogenetic analyses.

The paper develops an automated software tool for processing single-molecule force spectroscopy data, improving efficiency and reducing errors in fitting force-extension curves.

This paper introduces PS-ApTCs, a novel PROTAC design using aptamers for spatioselective degradation of nucleocytoplasmic shuttling proteins, showing enhanced efficacy and synergistic effects in cancer therapy.

The paper identifies the PNPO-PLP axis as a mechanism for sensing prolonged hypoxia by regulating lysosomal activity in macrophages, leading to altered inflammatory responses.

This study shows YAP forms organized condensates under Hippo pathway and actin tension, which stabilize YAP and recruit coactivators to enhance transcription.

This study evaluates the impact of Fcγ receptor affinity on CAR T cell efficacy and safety, finding that moderate affinity provides optimal antitumor activity while high affinity causes toxicity.

This study identifies BUD31 as a splicing factor that promotes ovarian cancer by maintaining anti-apoptotic BCL2L12 expression through exon inclusion.

This study shows mitotic chromosomes scale with cell size and nucleo-cytoplasmic ratio in Xenopus, distinct from other subcellular structures, through mechanisms involving condensin I and importin pathways.

This paper introduces a method using MRI and neural ODEs to model gastric motility and anatomy in rats, revealing functional regions and muscle activity patterns.