Z. Zhang

This study identifies the transcription activation domain and interaction region of EcaICE1 with EcaSIZ1 in Eucalyptus camaldulensis, revealing potential SUMOylation pathway similarities to Arabidopsis thaliana.

This study compares microbial composition in floor and air dust from university dormitories, showing significant differences that affect downstream microbiome analysis.

This paper introduces a drug discovery platform called SPEED that uses epitope editing to screen small molecules for altering antibody-epitope interactions and validates its application for Aβ species.

The paper develops a luciferase-based murine model and cell assay to evaluate the efficacy of MetRS inhibitor 1717 against Giardia lamblia, showing its potent in vivo activity.

This study analyzes 2,152 antibody repertoires to identify key features of B cell biology, revealing gene usage patterns, sex preferences, and mutability mechanisms in the antibody repertoire.

The paper introduces a pinhole optical trap that extends photobleaching lifetime by separating trap light from fluorescence illumination using wavefront engineering.

This study identifies TMEM-131 family proteins as conserved regulators of collagen assembly and secretion across species, showing their role in ER stress and collagen production.

This study identifies GATA3 and AP1-driven enhancer reprogramming as a mechanism promoting phenotypic plasticity and endocrine resistance in breast cancer.

This paper proposes a strategy to select crop varieties based on yield factors and meteorological predictions, showing 70% and 50% success rates in two pilot regions for soybean variety selection.

This study investigates the role of ASK1/p38-mediated NLRP3 inflammasome signaling in diabetic retinopathy, showing its contribution to inflammation and aberrant retinal angiogenesis.

This study shows that CHL1 overexpression reverses chemoresistance to cisplatin and paclitaxel in lung cancer by inhibiting the Akt pathway.

This study develops a rapid and efficient cowpea transformation system using embryonic axis explants, achieving transgenic shoot frequencies of 4.5 to 37%.

The paper examines the roles of three wheat glutamine synthetase isozymes in nitrogen assimilation and translocation, showing distinct functions and synergistic effects.

The paper analyzes oral microbiome data from the Earth Microbiome Project to show its distinct composition, lower diversity, and environmental correlations.

The paper investigates 5-hydroxymethylcytosine (5hmC) as a potential biomarker for pancreatic cancer, showing distinct distributions in tumor and adjacent tissues.

The paper curates a database of phage-host receptor interactions and finds that viral receptors, both in phages and mammalian viruses, are central in host protein-protein interaction networks.

The paper isolates and characterizes seven phages infecting Roseobacter RCA lineage bacteria, revealing genomic diversity and abundance in marine virosphere.

The paper shows that iron-deficiency and estrogen increase transferrin, leading to hypercoagulability and worsened ischemic stroke.

The paper uses gold nanorods to track fluid dynamics above swarming bacteria, revealing superdiffusive transport flows that enable long-range material transport and population-level communication.

This study identifies ANP32A and ANP32B as essential for influenza A virus polymerase activity, showing species-specific roles and mutations affecting viral replication.

The paper shows that Streptomyces coelicolor colonies use division of labour to enhance antibiotic production by generating specialized mutants that trade individual fitness for increased secondary metabolite diversity and yield.

The paper investigates how protein-protein interactions in E. coli's PTS system affect sugar transport and phosphorylation, showing both enhancement and inhibition of different PTS permeases.

The paper shows Tyr1 phosphorylation directs P-TEFb to phosphorylate Ser2 on RNA polymerase II CTD, altering its specificity and expanding CTD modification coding potential.

This study evaluates the efficacy and adverse effects of antibiotics in treating M. abscessus pulmonary disease, finding that four antibiotics correlate with treatment success but are associated with severe side effects.

The paper shows that protoplast formation in Kitasatospora viridifaciens causes genetic changes including megaplasmid loss and chromosomal lesions linked to insertion sequences.

This study investigates hybrid fitness in yeast under environmental stress, finding selection against heterozygosity and positive epistasis between divergent species.

This study designs and characterizes bifunctional ligands that induce K-Ras association with immunophilin proteins, showing their efficacy in blocking B-Raf interaction and suggesting therapeutic potential for Ras-driven cancers.

This study characterizes the colonization dynamics of Rhodopseudomonas palustris GJ-22 on tobacco phyllosphere and shows it induces plant resistance to Tobacco mosaic virus.

This study uses DNA-origami structures to measure lipid transfer distances mediated by the SMP domain of E-Syt1, supporting a shuttle model over a distance exceeding the SMP dimer length.

This study identifies SKI-73 as a CARM1 chemical probe that reduces breast cancer cell invasion by altering epigenetic plasticity, distinct from CARM1 knockout effects.