Mark H. Ellisman

The paper maps synaptic connectivity patterns in the SCN core and shell using EM techniques, showing the shell receives denser mRGC inputs than the core.

The paper tracks single HSPCs in zebrafish using light and electron microscopy to identify a new niche cell type and resolve their ultrastructural interactions.

The paper analyzes mitochondrial morphology in mouse cerebellum neurons using 3D TEM data to quantify structural features that influence metabolic output.

The paper systematically analyzes the morphology and morphometry of Drosophila olfactory receptor neurons using electron microscopy, revealing novel features and providing a dataset for future studies.

The paper demonstrates improved signal-to-noise and resolution in EFTEM elemental mapping by using lower energy-loss N4,5 edges instead of core-loss M4,5 edges for lanthanide detection.

Seven genes, including ftsZ, sepF and five of unknown function, are jointly required to restore near-normal morphology and division in the minimal cell JCVI-syn3.0.

The paper investigates how a motor neuron dynamically switches roles across behaviors without changing its anatomical connections by analyzing circuit anatomy and activity patterns.

The paper develops a genetic probe to label and image glutamatergic synaptic vesicles using 3D electron microscopy and deep learning.

This study shows that Aβ-induced synaptic injury in hippocampal neurons is mediated by presynaptic APP expression, as demonstrated by orientation-specific LTP reduction and synaptic loss.

CDeep3M-Preview allows users to test pre-trained neural networks on their data or public datasets via an online tool to improve reproducibility and biological insights.

The paper investigates the mechanisms and organization of clathrin transport and presynaptic targeting in neurons, revealing stable transport-packets and their role in synaptic clathrin organization.

This study shows that class IIa HDACs 4 and 5 regulate early response gene expression during learning, affecting memory formation and synaptic function.

The paper demonstrates asymmetric ephaptic inhibition between olfactory receptor neurons in Drosophila, showing that the larger neuron in a pair dominates the interaction.

The paper combines serial electron microscopy with electrophysiology to confirm, challenge, and discover synapses in the leech ganglion, demonstrating the value of integrating connectomics with physiological studies.

This study describes the directed evolution of a split APEX peroxidase, demonstrating its reconstitution and functionality in different cellular contexts.