Peter W. Harrison

Salmonids reveal principles of regulatory evolution following autotetraploidization

The paper studies gene regulatory evolution in salmonids after autotetraploidization, finding that it is influenced by developmental and tissue-specific factors, with constraints at advanced embryogenesis.

Empowering bioinformatics communities with Nextflow and nf-core

This paper discusses the adoption of Nextflow and nf-core frameworks to standardize bioinformatics pipelines, improving collaboration and interoperability across research communities.

Differences in maternal diet fiber content influence patterns of gene expression and chromatin accessibility in fetuses and piglets

This study shows that high-fiber maternal diets alter gene expression and chromatin accessibility in fetuses and piglets, improving metabolic health and immune tolerance.

The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics

The paper describes the European Reference Genome Atlas (ERGA) pilot project, which tests a decentralized model for producing high-quality reference genomes across 98 European species.

Mobilisation and analyses of publicly available SARS-CoV-2 data for pandemic responses

The paper describes open data sharing, analysis tools, and lessons learned from the European COVID-19 Data Platform's SARS-CoV-2 data collection and analysis efforts.

Population-scale proteome variation in human induced pluripotent stem cells

The paper characterizes proteome variation across 202 human iPSC lines, identifies 700 pQTLs, and links pQTLs to disease-associated GWAS variants.

Single-cell RNA-seq of differentiating iPS cells reveals dynamic genetic effects on gene expression

The paper uses single-cell RNA-seq of differentiating iPS cells from 125 donors to identify expression quantitative trait loci influencing gene expression during endoderm differentiation.

The COMPARE Data Hubs

The paper describes an informatics platform for structured data storage and pre-publication sharing of pathogen sequencing data with stakeholders.