Ivan Mikičić

This study shows that phosphorylation of Z granule components regulates germ granule organization and RNAi inheritance in C. elegans.

The paper uses pulsed-SILAC in single mouse embryos to study protein synthesis dynamics and phosphosite regulation during early embryogenesis, revealing active maternal proteome synthesis and post-translational regulation.

The paper shows that branching of polyubiquitin chains on PCNA, mediated by UBE2K, orchestrates the DNA replication stress response by promoting re-priming of stalled forks and requiring BRCA1-dependent repair.

This study identifies Myo6's role in DSB repair by interacting with KU70/80 and VCP, facilitated by F-actin, to extract the KU70/80 complex from chromatin.

The paper shows that the newt Pleurodeles waltl maintains telomeres without telomerase, using ALT for whole-organism telomere length preservation.