The Role of Locus Coeruleus and Substantia Nigra/Ventral Tegmental Area activity in Reward and Salience Processing: A High-Resolution fMRI Study
Julie M. Hall, Nanne Kukkonen, Eleni Prinea, Judith Schomaker, Ruth M. Krebs
This study uses high-resolution fMRI to show that SN/VTA and LC activity differ in their response to rewarded versus visually salient stimuli, indicating distinct roles in reward and salience processing.
bioRxiv · Oct 14, 2026 · PreprintNeuroscience