Xenopus

This study uses single-cell RNA sequencing to identify cell types and differentiation trajectories in frog lungs, revealing functionalization for air breathing and evolutionary insights.

The paper identifies high-impact DUBs and their substrates using Xenopus egg extract and proteomics, revealing substrate characteristics influencing DUB specificity.

This study investigates how DNA mismatches affect nucleosome mechanical stability and DNA exposure using single-molecule techniques, finding that C-C mismatches increase stability and reduce accessibility.

The paper introduces nanobodies that track or inhibit nuclear pore complex (NPC) assembly by targeting Nups and solving challenges in NPC detection and assembly inhibition.

This study identifies BD1047 as a direct inhibitor of GIRK channels, showing stronger inhibition of GIRK4 than GIRK2 and revealing structural determinants involving Leu77 on GIRK4.

The paper shows that glutamylation of acidic IDRs in Npm2 and Nap1 enhances their DNA mimicry function, improving histone chaperone efficiency in nucleosome assembly.

This study investigates factors influencing cervical vertebrae morphology in parrots, finding that phylogeny, allometry, integration, diet, and tripedal locomotion significantly affect shape, but diet and locomotion have weak influences with high morphospace overlap.

The paper introduces a fast proteomic method using CE-DIA MS to profile the subcellular proteome of single cells with high sensitivity and coverage.

The paper investigates cell-cell contacts and pericellular matrix in Xenopus gastrula chordamesoderm, showing that adhesion is mediated by pericellular matrix and that contact abundance decreases with adhesion factor depletion.

This study investigates how PKA inhibition and Cdk1 activation interact to regulate oocyte meiotic maturation, revealing two waves of translation and feedback loops that drive the G2/M transition.

This study investigates the roles of MRN and 9-1-1 complexes in ATR checkpoint activation and DNA end resection using Xenopus egg extracts.

This study investigates microbial associates of the elm leaf beetle, finding no resident bacteria but persistent fungi that may benefit the insect's performance.

This study identifies ABHD2 as an essential co-receptor for mPRβ to trigger meiosis via PLA2 activity in Xenopus oocytes.

This paper identifies ORI-TRN-002 as a novel AQP4 inhibitor with improved solubility and low protein binding, potentially useful for antiedema therapy.

This study investigates the role of Xenopus laevis mast cells in defending against chytrid fungus infections, finding they reduce inflammation and protect skin microbiomes.

This paper identifies a novel tamanavirus in European common frogs, RaTV, which encodes a divergent XRN1-resistant RNA element similar to flaviviruses.

This study profiles the transcriptome of a T6SS core gene mutant in Xanthomonas perforans to identify regulators affecting virulence, metabolism, and other functions.

This study compares two studies on OCT4 and LIN28B nucleosome interactions, finding that nucleosome positioning and H3 K27 acetylation do not significantly affect OCT4 binding.

This study identifies AvrE/DspE-family effectors as water/solute-permeable channels that facilitate bacterial virulence by causing host cell swelling and death.

This study investigates the antimicrobial activity of Xenopsylla cheopis attacins against Yersinia pestis, showing they inhibit colony formation and induce oxidative stress without causing immediate membrane damage.

The paper analyzes color evolution across five bird clades, finding that new color mechanisms enable new color space occupancy but not increased diversity, and that interpatch variation diverges from interspecies trends in males.

This study evaluates engineered Cas12a variants for gene inactivation in Xenopus laevis, finding that Cas12a-Ultra achieves high efficiency at low temperatures.

This study shows that AK7 deficiency in Xenopus leads to ciliary defects, reduced centriole numbers, and impaired mucociliary flow, linking AK7 to primary ciliary dyskinesia.

This study identifies FAM122A's role in inhibiting PP2A-B55 to initiate mitosis, showing its necessity in C. elegans and Xenopus systems.

This study investigates cilia regeneration in Xenopus multiciliated cells, showing delayed TZ assembly and insights into cilia length regulation.

The paper shows that neighbor cells restrain furrowing during epithelial cytokinesis by generating resistive forces through contractility and stiffness.

This study shows that PFOS exposure disrupts oligodendrogenesis and myelin function, impairing remyelination and potentially contributing to myelin disorders like multiple sclerosis.

The paper shows that BRME1 disrupts the HSF2BP-BRCA2 ring complex, preventing BRCA2 degradation and promoting homologous recombination in meiosis.

The paper shows nuclear growth and import can be uncoupled, suggesting chromatin mechanical properties drive nuclear growth rather than import alone.

The paper shows G-loop structures suppress mutagenic G4s by promoting RNA transcript hybridization and DNA synthesis, preventing genomic instability.