Advanced MRI Techniques and Applications

Field-Correcting GRAPPA (FCG): a technique to correctspatiotemporal-varying phase errors in Echo Planar Imaging

This paper introduces FCG, a technique that corrects spatiotemporal-varying phase errors in EPI using an MLP, improving image quality on high-performance systems.

Cumulative Transfer Function for Assessment of MRI-Induced RF Heating Risk in Pediatric Patients Implanted with Bifurcated Leads

This paper develops and validates a cumulative transfer function (cTF) framework to improve RF-heating risk assessment for bifurcated cardiac leads in MRI, showing significant error reduction compared to single-branch approximations.

Quantification of cardiac-locked brainstem velocity at high resolution based on retrospectively-gated DENSE MRI at 7T

This paper introduces a method to measure high-resolution cardiac-locked brainstem velocity using DENSE MRI at 7T, revealing a double-peak pattern of motion.

A realistic in-silico brain phantom for quantifying susceptibility anisotropy-induced error in susceptibility separation

The paper creates an in-silico brain phantom to evaluate how susceptibility anisotropy affects susceptibility separation algorithms, finding increased error in negative susceptibility estimates with anisotropy.

Challenges and Solutions in Quantifying Brain β-Hydroxybutyrate (BHB) with 1H-MRS Following Oral Keto-Ester Consumption

This study quantifies brain β-hydroxybutyrate (BHB) and 1,3-butanediol (BD) using J-difference edited 1H-MRS, revealing BD contributes significantly to signals traditionally attributed to BHB.

DATA-DRIVEN IDENTIFICATION OF SEX DIFFERENCES IN CEREBRAL BLOOD FLOW USING ARTERIAL SPIN LABELLING AND EXPLAINABLE ARTIFICIAL INTELLIGENCE

This study identifies sex differences in cerebral blood flow using explainable AI and finds perfusion-based biomarkers in frontoparietal and default mode networks.

Reduced Blood Flow in Deep White Matter During Hypercapnia Revealed by Multi-Delay pCASL in Healthy Young Adults

This study uses multi-delay pCASL to show that deep white matter has little to no increase in blood flow during hypercapnia, unlike other brain regions.

Sex differences in brain metabolism assessed with whole-brain magnetic resonance spectroscopic imaging

The paper uses magnetic resonance spectroscopic imaging to identify sex differences in brain metabolites across multiple cohorts, finding a consistent male higher tNAA/tCr ratio in gray and white matter.

Revisiting the auditory hemodynamic response function in the era of fast fMRI

This study uses fast fMRI to characterize voxelwise auditory hemodynamic response functions (HRFs) and finds diverse, reliable, and regionally specific HRFs not captured by standard models.

Dissociation between hemodynamic and neurochemical responses during chemogenetic modulation of cortical circuits in rats

This study examines hemodynamic and metabolic responses in rat motor cortex after chemogenetic activation, finding strong BOLD effects but delayed metabolic changes.

Opportunities and pitfalls in preclinical cerebral blood flow mapping using arterial spin labelling MRI: insights from multicentre data

This paper identifies sources of variability in cerebral blood flow measurements using arterial spin labelling MRI in rodents and calls for standardized practices to improve reproducibility.

ComCat: Combating Covariate Effects in Brain Analysis

ComCat improves brain analysis by reducing unwanted variability from heterogeneous datasets, outperforming existing methods in brain age prediction across multiple datasets.

Multi-Parametric Phase-Cycled Balanced Steady-State Free Precession Brain Tissue Characterization in Relapsing-Remitting Multiple Sclerosis

The paper evaluates quantitative MRI metrics in RRMS patients and healthy controls to identify white matter alterations using a multi-parametric pc-bSSFP framework.

SNR Enhancement Considerations for Loop Receive Coils at Ultra-High Fields

This study quantifies parasitic losses in UHF MRI receive coils and shows how they reduce predicted SNR, providing guidance for improving coil design.

Deep Learning-Based Reconstruction: Model Comparison for Variable-Density GRAPPA 1H MRSI

This paper compares deep learning models for improving 1H MRSI reconstruction, finding that U-Net outperforms MultiNet in reducing lipid artifacts and improving metabolite map fidelity.

Scout-based Multi-Echo NAvigator (SMENA) for high temporal resolution motion and B0 estimation and correction: applications to multi-echo GRE and EPTI

SMENA estimates motion and B0 inhomogeneity with high temporal resolution, improving image quality in MRI by correcting both factors simultaneously.

FAST BOLD FMRI REVEALS THE SPATIOTEMPORAL COMPLEXITY OF NEUROVASCULAR COUPLING ALTERATIONS IN CEREBRAL SMALL VESSEL DISEASE

The paper uses fast BOLD fMRI to study neurovascular coupling in CADASIL patients, finding altered BOLD response amplitude and timing indicative of early neurovascular impairment.

Receive-Only Coupled Wireless Radiofrequency Probe for Endocavity MR Imaging Using a pTx System

The paper demonstrates a wireless RF resonator probe with a dual-drive pTx system to enhance MRI SNR in a localized region while minimizing transmit-field interactions.

Cerebrovascular pulsatility differs across vascular compartments and is altered by hypercapnic stimuli: a BOLD fMRI study

This study introduces a cardiac-specific BOLD fMRI-based pulsatility index, validates its sensitivity to hypercapnia, and shows its correlation with vascular reactivity and venous blood volume.

Neuroendocrine influences on dynamic cerebrovascular function and implications for functional MRI

This study examines how menstrual-related ovarian hormones affect dynamic cerebrovascular function using MRI and hormone measurements, finding significant neuroendocrine influences on vascular reactivity and hemodynamic response.

Methylmalonic acid: a new target for Hadamard-edited MRS

This paper develops a Hadamard-edited MRS method to separate methylmalonic acid and lactate signals, demonstrating its effectiveness in vivo for MMAemia diagnosis.

Infra-slow (<0.1 Hz) modulation of human brain pulsations in awake and sleep states

This study investigates cross-frequency oscillatory interactions in brain pulsations during awake and NREM-sleep states, revealing directional coordination mechanisms between infra-slow, respiratory, and cardiovascular oscillations.

An open-source stereotaxic container with an integrated cutting guide for human brain fixation during magnetic resonance imaging and sectioning for histology

This paper introduces a stereotaxic container for human brain fixation that enables precise MRI-to-histology alignment during postmortem studies.

Short T1 Fraction as a Marker of Myelin Content: Evidence from Postmortem MRI and Histology

This study investigates the short-T1 fraction as a biomarker of myelin content using postmortem MRI and histology, showing strong correlations with myelin water imaging and histological markers.

An RF coil array system for in vivo & ex vivo non-human primate brain studies at 10.5 Tesla

The paper develops an RF coil array system for high-resolution in vivo and ex vivo non-human primate brain imaging at 10.5 Tesla, achieving improved spatial resolution and imaging capabilities.

Voxel-wise tracer kinetic model selection for DCE-MRI measurements of blood-brain barrier leakage

This study applies voxel-wise tracer kinetic model selection to DCE-MRI data to improve sensitivity in differentiating normal from pathological tissue compared to the Patlak model.

Toward Large-Scale Preclinical Neuroimaging: Quantifying Inter-Scanner Variability in Mouse Brain MRI

This study quantifies inter-scanner variability in mouse brain MRI using phantoms and ex vivo specimens, finding small differences in ADC, volume, and quantitative maps.

Superpixel-ComBat multi-site harmonization of unpaired T1W MRI data in Huntingtons disease

This paper adapts Superpixel-ComBat to harmonize unpaired multi-site T1W MRI data in HD, improving image quality and enabling unified VBM analyses across scanners.

Examining excitation-inhibition modulation during social processing using functional Magnetic Resonance Spectroscopy

This study uses fMRS to examine if socially-laden stimuli modulate excitation-inhibition neurometabolites and relate to social function, finding minimal shifts in Glx and GABA+.

Metabolic modelling and time-resolved mapping of glucose oxidative metabolism in rats brain by indirect deuterium detection with 1H-FID-MRSI at 9.4T

This study uses dynamic 1H-[2H]-FID-MRSI and a metabolic model to quantify glucose oxidative metabolism in rat brain regions during 2H-Glc infusion.