Neurobiology and Insect Physiology Research

The paper shows T3 neurons in Drosophila mediate object tracking saccades by responding to visual stimuli and modulating saccade frequency through silencing or optogenetic manipulation.

The paper investigates the role of the transcription factor Cut in the development and function of compound eyes in two insects with different optical systems, finding it critical for lens and photoreceptor formation.

This study identifies a descending inhibitory mechanism of nociception in Drosophila mediated by the evolutionarily conserved neuropeptide DSK, analogous to the mammalian CCK system.

This study investigates how projection neurons in Drosophila establish wiring specificity in the olfactory map through lineage, birth order, and dynamic dendrite remodeling during development.

The paper identifies two downstream neuron groups modulated by tachykinin in Drosophila, showing how neuropeptide levels affect aggression through distinct receptor-mediated pathways.

The paper identifies how temperature stimuli are encoded in the gene expression of C. elegans thermosensory neurons, revealing transcriptional dynamics that drive plasticity.

The paper identifies molecular mechanisms by which social experience and pheromone signaling modulate neuromodulatory gene expression in Drosophila sensory neurons through RNA-seq analysis.

The paper identifies ascending neurons in Drosophila that encode high-level behaviors and project to brain regions involved in sensory integration and action selection.

The paper models the Drosophila mushroom body to show how sparse synaptic connectivity enables efficient memory storage through stochastic input integration.

The paper maps the synaptic-resolution connectome of a Drosophila larva brain, identifying neuron types, circuit motifs, and structural features.

This study shows how the metabolic enzyme OGT regulates chromatin accessibility and transcription in Drosophila gustatory neurons to mediate sensory adaptations to a high sugar diet.

This study investigates how geosmin affects honey bee defensive behavior and neural responses, finding concentration-dependent suppression of alarm pheromone-induced aggression.

The paper introduces two open-source tools to automatically measure compound eye optics from 2D images and 3D CT data, validated on insect specimens.

The paper studies how C. elegans chemosensory neurons encode olfactory information through ensemble activity and natural stimuli.

This paper investigates the effects of altering lactate metabolism in Drosophila neurons and glia on aging and memory, finding age-dependent impacts on survival and memory.

The paper measures voltage and calcium signals in Drosophila T4 neurons and shows calcium signals have higher direction selectivity than voltage signals.

The paper identifies heterogeneous clock and dopaminergic cell types in Drosophila using single-cell sequencing and shows connectivity molecules best characterize these neuron groups.

The paper introduces genetically targeted membrane tethers for rapid in vivo neuronal labeling in Drosophila using fluorescent dyes.

The paper compares two models of global inhibition in fruit fly head-direction circuits, finding that a hybrid model performs best across multiple tests.

The paper proposes a linear discriminant analysis model of imbalanced associative learning in the mushroom body compartment, explaining how dopamine neurons modulate synaptic plasticity.

The paper shows olfactory receptor neurons generate multiple response motifs that enhance coding dimensionality for odor classification and navigation.

The paper develops a genetically encoded calcium sensor for imaging neural activity in honey bees and uses it to study odor coding in different brain regions.

This study shows ecdysone acts through cortex glia to regulate sleep in Drosophila by modulating lipid metabolism.

This study identifies genes and pathways that interact with early-life nutrition to influence sleep behavior and brain morphology in Drosophila.

The paper shows that serotonin signaling modulates the coincidence time window in Drosophila associative learning by a feedback circuit involving ACh and 5-HT.

The paper examines the developmental origins and metamorphic fates of neurons in the larval and adult mushroom body circuits of Drosophila to understand how a functional larval brain is formed from a reduced set of neurons.

The paper shows that the attP40 transgenic landing site in Drosophila disrupts Or47b olfactory receptor neuron glomerular organization, suggesting potential genetic interactions or background effects.

The paper identifies a feedforward circuit between dopamine subsystems in Drosophila that is essential for second-order conditioning, mediated by a key interneuron.

The paper identifies chloride-dependent mechanisms in Drosophila CIII neurons that underlie cold-evoked behavior and neuropathic sensitization.

This study identifies how prior experience modulates sensory gain control in C. elegans ASH neurons, altering their response to odor concentration changes and enhancing odor avoidance behavior.