Neurobiology and Insect Physiology Research

The paper identifies sex-specific VC neurons in C. elegans that are mechanically activated and facilitate serotonin-induced egg laying by coordinating muscle contractility and mechanosensory feedback.

This paper identifies a neuroendocrine pathway in Drosophila that modulates osmotic and ionic stress tolerance through the interaction of Corazonin and CAPA neuropeptides.

The paper uses Targeted DamID to profile rare Drosophila sensory neurons, identifying transcription factors and guidance molecules involved in neuron fate and wiring.

The paper uses GWAS in Drosophila to identify molecular pathways controlling weight and exercise-induced weight changes, finding CNS involvement and signaling pathway importance.

This study uses thermal laser ablation in C. elegans to investigate the origins of seizure-like convulsions in a gain-of-function mutant.

The paper analyzes the antennal transcriptome of Harmonia axyridis to identify chemosensory genes, revealing sex-biased expression of some odorant-binding proteins and odorant receptors.

This study identifies a pathway linking the dopamine receptor DOP-1 to a sleep mechanism that modulates sustained swimming in C. elegans.

This study shows that memory consolidation in Drosophila involves structural and functional reorganization of a specific neural circuit in the mushroom body.

This study identifies the genetic architecture underlying larval aggregation behavior in Drosophila melanogaster using natural populations and genetic approaches.

The paper uses diffusion condensation to analyze the C. elegans nerve ring neuropil, revealing its stratified structure and developmental principles.

This study identifies syp as a gene regulating Starvation-Induced Hyperactivity in Drosophila through RNA-binding protein function and alternative splicing.

FlyBrainLab integrates neuroanatomical, neurogenetic, and electrophysiological data to enable interactive exploration and modeling of Drosophila brain circuits.

The paper identifies regulatory elements in Drosophila fruitless neurons that are differentially accessible and controlled by FruM, revealing cell-type-specific masculinization mechanisms.

This study identifies Drosophila Piezo as a mechanosensory receptor that controls meal size by detecting gut distension, with Piezo neuron activation reducing appetite and knockout increasing food intake.

The paper introduces the FLEA assay to measure incentive motivation in Drosophila by using electric shock as an aversive stimulus, revealing a novel role for neuropeptide F in processing electroshock.

The paper investigates how a motor neuron dynamically switches roles across behaviors without changing its anatomical connections by analyzing circuit anatomy and activity patterns.

The paper maps the postsynaptic connections of Drosophila mushroom body output neurons using trans-Tango, revealing convergent targets and a multilayer circuit for information integration.

This study investigates the role of Juvenile Hormone receptor components in male desert locust sexual maturation and finds that silencing these components disrupts reproduction and key physiological traits.

The paper generates single-cell transcriptomes of Drosophila olfactory receptor neurons across development and adulthood, revealing stable receptor expression and cell-type-specific transcriptomic features.

The paper describes a novel evolutionary structure of mushroom bodies in shore crabs, showing a departure from typical crustacean patterns with deep calyces and elaborate gyri.

This study shows that loss of dop-2 in C. elegans increases dopamine release and causes locomotory defects when exposed to ethanol.

The paper shows that fruM is critical during development for building a sex circuitry with reduced flexibility and enhanced efficiency, but its function in adulthood is minimal.

The paper models C. elegans thermotactic steering behavior using a neuroanatomical model and evolutionary algorithm, finding that persistent thermal signals modulate steering rates to guide movement toward a target temperature.

The paper presents a high-resolution EM dataset of Drosophila ventral nerve cord and develops GridTape for automated EM data collection, revealing a unique feedback pathway in motor control.

The paper identifies SRX-97 as a GPCR in C. elegans that mediates high-concentration benzaldehyde sensing in ASH neurons.

This study shows how food deprivation alters olfactory behavior in Drosophila larvae by changing neural processing in the antennal lobe through state-dependent circuit dynamics.

This study identifies bantam as a regulator of sleep in Drosophila by inhibiting specific wake-promoting neurons during the night.

This study uses kinematic analysis in Drosophila to assess developmental neurotoxicity, showing that motor dysfunction can indicate neurotoxic effects of chemicals.

The paper identifies a group of Drosophila central complex neurons that encode airflow direction and are necessary for proper orientation to airflow.