Advanced Neuroimaging Techniques and Applications

Loss of Brain Structural qMRI Signatures in Aging

This study examines age-related changes in brain microstructure using qMRI, finding increased regional similarity and individual variability in older adults.

Functional connectivity, tissue microstructure and T2 at 11.1 Tesla distinguishes neuroadaptive differences in two traumatic brain injury models in rats: A Translational Outcomes Project in NeuroTrauma (TOP-NT) UG3 phase study

This study uses multimodal neuroimaging to compare functional connectivity and tissue microstructure in two rat TBI models, finding distinct neuroadaptive differences.

Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI

This paper introduces a method to map cortical-layer specific area boundaries in primates using myelin MRI, revealing a 182 area/subarea partition in macaques with high homology to human myelin maps.

Beyond the Resection: Surgical White Matter Disruption alters Non-Resected Brain Anatomy

This study investigates postoperative atrophy in non-resected brain regions following resective neurosurgery, linking it to transneuronal degeneration and showing that structural network reorganisations may be artifacts of image processing.

Multimodal imaging of human fetal brain development at the mesoscopic scale using 11.7 T ex vivo MRI

The paper presents a new MRI dataset of human fetal brains at high resolution, covering gestational ages 18, 27, and 31 weeks, with multimodal imaging data for neurodevelopmental research.

Directed connectomes across species reveal conserved and divergent pathways of neural signaling

The paper constructs directed connectomes across species using viral tracing and diffusion MRI to identify conserved and divergent neural pathways.

VASAL: A Vascular Substrate Algorithm to Generate Microvascular Network Phantoms

VASAL generates realistic microvascular network phantoms and simulates dMRI signals, showing compatibility with IVIM model assumptions and vascular structure effects on diffusion.

Benchmarking Orientation Distribution Function Estimation Methods for Tractometry in Single-Shell Diffusion Magnetic Resonance Imaging - An Evaluation of Test-Retest Reliability and Predictive Capability

This paper evaluates ODF reconstruction methods for single-shell dMRI, finding SS3T provides reliable and predictive WM bundle segmentation with lower angular resolution data.

The cellular associates of late life changes in white matter microstructure

This study identifies genetic and cellular factors associated with age-related changes in white matter microstructure using GWAS and transcriptomic data from UK Biobank.

Complex Patterns of Altered White Matter Structural Connectivity within a 'subjective valuation network' in Treatment-Resistant Depression

This study identifies altered white matter structural connectivity in specific subcircuits of the subjective valuation network in treatment-resistant depression, linking these changes to anhedonia and treatment resistance.

Differential microstructural development within sensorimotor cortical regions: A diffusion MRI study in preterm and full-term infants

This study uses diffusion MRI to compare microstructural development in sensorimotor cortical regions between preterm and full-term infants, finding region-specific deviations in preterm infants.

Robust constrained weighted least squares for in vivo human cardiac diffusion kurtosis imaging

This paper develops RCWLS for cardiac DKI to improve signal fitting by combining robust estimation with convexity constraints, showing it reliably captures expected kurtosis patterns and corrects corrupted regions.

Supervised white matter bundle segmentation in glioma patients with transfer learning

This paper evaluates transfer learning for adapting a deep learning model trained on healthy data to segment white matter bundles in glioma patients, finding performance drops due to domain shift and partial success of transfer learning.

Multivariate white matter microstructure alterations in older adults with coronary artery disease

This study identifies white matter microstructural alterations in older adults with coronary artery disease using a multivariate approach and links them to cognitive performance.

Multimodal, multifaceted Imaging-based Human Brain White Matter Atlas

The paper develops a multimodal white matter atlas using 7-Tesla MRI to improve functional understanding of brain white matter, showing high consistency and reliability.

Demystifying The Myelin g ratio: Its Origin, Derivation and Interpretation

The paper challenges assumptions about the myelin g ratio, showing it can inaccurately represent myelin structure in non-steady states and proposes alternative metrics.

Characterizing neuronal cell bodies in human postmortem cerebral white matter tracts

The paper validates the presence of neuronal cell bodies in human long-range white matter tracts, finding higher densities in the uncinate fasciculus compared to other regions.

White matter microstructure changes across the lifespan: a meta-analysis of longitudinal diffusion MRI studies

This paper meta-analyzes longitudinal diffusion MRI studies to show how white matter fractional anisotropy changes with age and identifies genetic influences on these changes.

Disentangling the influences of pre- and postnatal periods on human cortical microstructure

The paper examines how pre- and postnatal factors influence human cortical microstructure using MRI data from neonates, finding distinct effects on microstructural density and homogeneity.

Mapping the coupling between tract reachability and cortical geometry of the human brain

This study maps the coupling between cortical geometry and white matter tract connectivity, showing how these aspects jointly shape brain function.

Deep generation of personalized connectomes based on individual attributes

The paper introduces a deep learning model to generate individual connectomes from personal attributes and shows it can accurately replicate empirical connectomes from the UK Biobank.

Complementary MR measures of white matter and their relation to cardiovascular health and cognition

The paper identifies latent factors underlying white matter metrics using MRI data from a cohort of healthy adults and links these factors to cardiovascular health and cognitive performance.

Lifespan Normative Models of White Matter Fractional Anisotropy: Applications to Early Psychosis

This paper develops lifespan normative models of white matter fractional anisotropy using diffusion MRI data and applies them to identify white matter deviations in early psychosis.

Towards an informed choice of diffusion MRI image contrasts for cerebellar segmentation

This study evaluates diffusion MRI contrasts for cerebellar segmentation, finding that spherical mean images outperform traditional microstructure maps.

Estimating Brain Similarity Networks with Diffusion MRI

This paper introduces diffusion similarity networks (DSNs) using diffusion MRI to map brain structural organization, showing improved sensitivity to age, cognition, and sex compared to prior methods.

The superficial white matter in language processing: Broca's area connections are bilaterally associated with individual performance in children and adults

This study examines the role of superficial white matter connections of Broca's area in language performance across children and adults, finding bilateral associations with language tasks.

Validation of Structure Tensor Analysis for Orientation Estimation in Brain Tissue Microscopy

This study evaluates structure tensor analysis for estimating fiber orientations in brain imaging, showing parameter sensitivity in crossing fibers and anisotropic data.

Assessing Quantitative MRI Techniques using Multimodal Comparisons

The paper analyzes quantitative MRI metrics in healthy adults to understand their relationships and potential for uncovering cortical gradients.

Passive water exchange between multiple sites can explain why apparent exchange rate constants depend on ionic and osmotic conditions in gray matter

Mapping the Microstructure of Human Cerebral Cortex In Vivo with Diffusion MRI

This paper maps human cerebral cortex microstructure using diffusion MRI, identifying 21 metrics linked to cytoarchitecture, function, and cognition, and showing their heritability and predictive power for age and cognition.