Advanced Neuroimaging Techniques and Applications

Reorganisation of Cortico-Hippocampal White Matter Pathways in Healthy Ageing: Evidence for Paradoxical Shifts in Structural Connectivity.

This study investigates age-related changes in hippocampal structural connectivity using advanced tractography, finding reduced connections to posterior regions and increased connections to anterior temporal areas in older adults.

Cross-species Standardised Cortico-Subcortical Tractography

This paper introduces standardized tractography protocols for mapping cortico-subcortical tracts in human and macaque brains, showing robustness and applicability across species.

Anatomy-to-Tract Mapping Infers White Matter Pathways Without Diffusion Streamline Propagation

This paper introduces Anatomy-to-Tract Mapping (ATM), a method that generates white matter streamlines directly from T1-weighted MRI without diffusion tractography, showing strong performance across multiple metrics.

High-resolution MRI Guided Whole Mouse Brain Cell Type Atlas using Deep Learning

This paper develops a deep learning framework combining high-resolution MRI and spatial transcriptomics to create a whole-brain mouse cell type atlas at 10 micrometer resolution.

In vivo Quantification of White Matter Pathways in the Human Hippocampus

This study quantifies human hippocampal white matter pathways in vivo using diffusion weighted imaging and a large sample, revealing monosynaptic and trisynaptic connections and linking pathway variability to cognitive abilities.

Myelinated fiber labeling and orientation mapping of the human brain with light-sheet fluorescence microscopy

The paper develops a method to label and map myelinated fibers in human brain tissue using light-sheet fluorescence microscopy and automated image analysis, enabling high-resolution structural characterization.

White Matter Tract Vulnerability to Amyloid Pathology on the Alzheimer's Disease Continuum

This study uses BUAN tractometry to assess how amyloid positivity affects white matter tracts in Alzheimer's disease, revealing localized microstructural changes associated with amyloid pathology.

Using Diffusion Transformers to Generate Synthetic Diffusion Scalar Maps for Data Augmentation

This paper generates synthetic brain MRI data using a Diffusion Transformer to augment neuroimaging datasets and improve dementia classification.

Deterministic versus Probabilistic Tractography: Impact on White Matter Bundle Shape

This study compares deterministic and probabilistic tractography methods for the left arcuate fasciculus across four datasets, finding probabilistic methods yield higher inter-subject shape similarity but may obscure subtle pathological variations.

Generating diffusion MRI scalar maps from T1-weighted images using Reversible GANs

This paper generates synthetic diffusion MRI scalar maps from T1-weighted images using RevGAN, showing they retain microstructural features and perform well in downstream tasks.

DTI versus NODDI White Matter Microstructural Biomarkers of Alzheimer's Disease

The paper compares DTI and NODDI models using dMRI data from ADNI participants to assess their ability to detect AD-related biomarkers like cognitive impairment and amyloid-beta/tau pathology.

White matter micro- and macrostructural properties in midlife individuals at risk for Alzheimer's disease: Associations with sex and menopausal status

Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications

The paper describes improvements in diffusion MRI processing for the HBCD study, introducing new software and observing developmental patterns in brain data.

MRI-based 3D Estimation of Skeletal Muscle Architecture and Strain during Contraction

This study uses MRI to estimate 3D skeletal muscle architecture and strain during contraction, revealing changes in fiber-tract length, pennation angle, and curvature.

On the replicability of diffusion weighted MRI-based brain-behavior models

This paper evaluates the replicability of diffusion-weighted MRI-based brain-behavior models and finds moderate replicability with small sample sizes, but higher replicability for trait-like phenotypes.

Non-invasive prediction of conduction velocities in the human brain from MRI-derived microstructure features at 7 Tesla

This paper develops a whole-brain model to predict conduction velocity from MRI-derived microstructural features, explaining 29% of variance in neurophysiological conduction velocity.

skiftiTools: An R package for reading, writing, analysing, and visualising, tract-based spatial statistics (TBSS) derived diffusion MR images

skiftiTools enables statistical analysis and visualization of TBSS-derived diffusion MRI data using R, supporting advanced modeling and data manipulation.

Imbalanced Brain Connectome: A Novel Link between Functional Somatic Disorders, Multiple Chemical Sensitivity, and Post-COVID patients

This study identifies reduced inter-hemispheric brain connectivity in patients with functional somatic disorders, multiple chemical sensitivity, and post-COVID-19 conditions compared to healthy controls.

End-to-end evaluation of white matter microstructure of the visual pathway in asymmetric glaucoma

This study evaluates white matter microstructure in asymmetric glaucoma using advanced diffusion MRI methods, finding significant diffusion metric differences and correlations with clinical parameters.

A Comparison of Skeletal Muscle Diffusion Tensor Imaging Tractography Seeding Methods

This study compares seeding methods for diffusion tensor imaging tractography in skeletal muscle, finding that voxel-based methods match the accuracy of aponeurosis-based seeding and offer workflow advantages.

Intracortical microstructure profiling: a versatile method for indexing cortical lamination

This paper introduces a method for profiling intracortical microstructure to assess laminar organisation, showing its robustness and reliability across different datasets and sites.

An anthropoid/strepsirrhine divergence in ventral visual stream connectivity

This study compares white matter connectivity in two anthropoids and one strepsirrhine using diffusion MRI, finding greater dorsal prefrontal innervation in anthropoids.

Resolving Cellular Morphology in the Human Brain with Multiparametric Diffusion MR Spectroscopy

This paper introduces multiparametric diffusion MR spectroscopy to estimate cell-type-specific morphology in the human brain by combining diffusion-time-dependent encoding with double-diffusion-encoded spectroscopy.

Submillimeter diffusion MRI using an in-plane segmented 3D multi-slab acquisition and denoiser-regularized reconstruction

This paper introduces a novel acquisition and reconstruction framework for submillimeter diffusion MRI, achieving high-quality images at 0.53 mm and 0.65 mm resolutions with reduced distortion and improved SNR.

Diffusion MRS tracks distinct trajectories of neuronal development in the cerebellum and thalamus of rat neonates.

This study uses diffusion-weighted MRS to track cell-specific developmental trajectories in the cerebellum and thalamus of rat neonates, revealing age-related changes in metabolite diffusion properties.

Impacts of perinatal factors on white matter outcome at 8 to 10 years by diffusion tensor imaging

The paper examines the impact of perinatal factors on white matter microstructure in children aged 8-10 years using diffusion tensor imaging.

Domain shifts in infant brain diffusion MRI: Quantification and mitigation for fODF estimation

This study evaluates deep learning models for fODF estimation in infant brain MRI, finding that U-Net performs best with fewer gradient directions, while MLP and Transformer improve with more directions.

Parallel Wires: A Conserved Principle of Contralateral-Ipsilateral Segregation in the Visual Corpus Callosum

The paper demonstrates that the visual corpus callosum uses segregated 'parallel wires' for contralateral and ipsilateral information flow, supported by fMRI and anatomical studies in humans and mice.

Microstructural organization of Superior Longitudinal Fasciculus and Cingulum Bundle support metacognition driven cognitive offloading

The paper investigates how white matter microstructural integrity in specific tracts relates to metacognition-driven cognitive offloading using diffusion tensor imaging.

Distinct cellular processes drive motor skill learning in the human brain

This study uses diffusion MRI and a new model to identify distinct cellular processes underlying motor skill learning in the human brain.