Neuroscience and Neural Engineering

Human-in-the-loop optimization of visual prosthetic stimulation

This paper optimizes visual prosthetic stimulation using patient feedback and Bayesian optimization, improving perceived image quality in healthy subjects.

pyNeurode: a real-time neural signal processing framework

pyNeurode provides a real-time spike sorting framework for neural signals with high accuracy and scalability, supporting up to 128 channels and integrating with Open Ephys.

Identification and assessment of systematic measurement error on electrophysiological recordings of neural cell cultures

The paper identifies systematic measurement errors in MEA recordings and shows how they affect data interpretation, proposing methods for detection and correction.

Tangential high-density electrode insertions allow to simultaneously measure neuronal activity across an extended region of the visual field in mouse superior colliculus

The paper describes a method to measure neuronal activity across a large region of the mouse superior colliculus using high-density electrodes and optogenetic tools for cell-type identification.

Ultra-flexible and Stretchable Intrafascicular Peripheral Nerve Recording Device with Axon-dimension, Cuff-less Microneedle Electrode Array

This paper develops a flexible microneedle electrode array for peripheral nerve recording, demonstrating reduced tissue encapsulation and chronic reactivity in rats.

Universal guide for skull extraction and custom-fitting of implants to continuous and discontinuous skulls

The paper provides a step-by-step guide for custom-fitting implants to skulls with continuous or discontinuous surfaces, using virtual bending and CAD tools, and demonstrates its application in rhesus monkeys.

The Hybrid Drive: a chronic implant device combining tetrode arrays with silicon probes for layer-resolved ensemble electrophysiology in freely moving mice

The paper introduces a new chronic implant device for mice that combines tetrode arrays and silicon probes to record layer-resolved neural activity in freely moving animals.

Nanoscale patterning of in vitro neuronal circuits

This paper develops a method to pattern neuronal circuits in vitro using nanoscale structures to guide synapse formation between isolated neuron groups.

Characterizing the short-latency evoked response to intracortical microstimulation across a multi-electrode array

The paper characterizes the short-latency neural responses to intracortical microstimulation using a multi-electrode array and describes the temporal dynamics of evoked activity.

Reversible edema following electric drilling of macaque craniotomy

The paper reports reversible edema in macaques after electric drilling for craniotomy, observed via MRI, and advises caution in electrophysiological recordings for 2-3 weeks post-surgery.

Intracortical microstimulation pulse waveform and frequency recruits distinct spatiotemporal patterns of cortical neuron and neuropil activation.

This study shows that different ICMS pulse waveforms and frequencies activate distinct patterns of cortical neurons and neuropil in mice, with frequency-dependent effects on population activity.

Stimulation-Evoked Effective Connectivity (SEEC): An in-vivo approach for defining mesoscale corticocortical connectivity

This paper introduces SEEC, a method using ICMS and multi-unit recordings to assess mesoscale effective connectivity in sensorimotor cortex of squirrel monkeys, showing stable short-latency responses correlated with anatomical connections.

A fully adapted headstage for electrophysiological experiments with custom and scalable electrode arrays to record widely distributed brain regions

This paper describes a low-cost, open-source headstage system for scalable electrophysiological recordings from multiple brain regions using custom electrode arrays.

An automated method for precise axon reconstruction from recordings of high-density micro-electrode arrays

This paper introduces an automated method to reconstruct axons and estimate action-potential propagation velocities from high-density microelectrode array recordings.

A toolbox for studying cortical physiology in primates

The paper develops a toolbox for studying cortical physiology in non-human primates, combining optical and electrophysiological techniques to monitor and modulate cortical function.

Multichannel optogenetics combined with laminar recordings for ultra-controlled neuronal interrogation

This paper develops thin optical fibers and integration techniques to enable large-scale neuronal recordings and ultrafast optogenetic inhibition in freely moving animals.

Engineered biological neural networks on high density CMOS micro electrode arrays

This paper describes a method to engineer biological neural networks on high-density CMOS microelectrode arrays to improve spatial resolution and axon guidance.

Extracellular and intracellular components of the impedance of neural tissue

This paper measures impedance of neural tissue across different preparations and shows frequency-dependent behavior that cannot be explained by resistive models, attributing it to ionic diffusion in Debye layers.

Similarities Between Somatosensory Cortical Responses Induced via Natural Touch and Microstimulation in the Ventral Posterior Lateral Thalamus in Macaques

The paper compares somatosensory cortical responses from natural touch and microstimulation in macaques' ventral posterior lateral thalamus, showing high correlation between the two.

Lussac: a fully-automated consensus method that increasesthe yield and quality of spike-sorting analyses

Lussac improves spike-sorting yield and quality by combining multiple analyses into an automated consensus method.

Large-scale neural recordings with single-cell resolution in human cortex using high-density Neuropixels probes

This paper describes a new high-density Neuropixels probe enabling single-cell resolution recordings from over 200 cortical neurons in humans during surgery, identifying eight distinct single unit classes.

ACCURATE DECODING OF THE SPINAL CORD OUTPUT IN HUMANS WITH IMPLANTED HIGH-DENSITY ELECTRODE ARRAYS

The paper develops a high-density electrode and methodology to decode up to 67 concurrently active motoneurons in humans with 99% accuracy, revealing population-level synaptic input and inhibition patterns.

A novel method for multi-scale recording of intracranial EEG through dynamic alteration of electrode surface area

This paper introduces a method to dynamically alter electrode size in vivo to study the impact of electrode size on intracranial EEG features across different brain regions.

The Layer 7 Cortical Interface: A Scalable and Minimally Invasive Brain-Computer Interface Platform

This paper introduces a minimally invasive brain-computer interface platform using thin-film electrodes and demonstrates its feasibility for high-density neural recording and stimulation in preclinical and clinical settings.

Topologically controlled circuits of human iPSC-derived neurons for electrophysiology recordings

The paper presents a method to create topologically controlled circuits of human iPSC-derived neurons for long-term electrophysiology recordings.

A multimodal 3D neuro-microphysiological system with neurite-trapping microelectrodes

This paper introduces a 3D neuro-microphysiological system with microelectrodes for high-throughput electrical recording and analysis of human neurons.

Full bandwidth electrophysiology of seizures and epileptiform activity enabled by flexible graphene micro-transistor depth neural probes

This paper introduces flexible graphene micro-transistor depth neural probes for recording infraslow and high-frequency neuronal activity in rodents, demonstrating their utility in epilepsy research.

Stoney vs. Histed: Quantifying the Spatial Effects of Intracortical Microstimulation

This paper uses computational modeling to resolve conflicting findings on how intracortical microstimulation (ICMS) intensity affects neural activation, showing increased activation density without increased volume.

Double-μPeriscope: a tool for multi-layer optical recordings, optogenetic stimulations or both

The paper introduces a tool for simultaneous optical recording and optogenetic stimulation in two cortical layers of mice.

Carbon Fiber Electrodes for Intracellular Recording and Stimulation

This study demonstrates that carbon fiber electrodes can record intracellular activity and stimulate neurons in intact nervous systems, offering a stable and scalable alternative to traditional methods.