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This study evaluates the acute biological response to Utah Optrode Array implantation in macaque cortex, identifying design parameters that minimize tissue damage and improve biocompatibility.

This study evaluates HA-binding peptides in vivo, showing D8 and YD8 preferentially accumulate in diseased bone, highlighting their potential for targeted therapies.

This paper demonstrates that anti-biofouling albumin amyloid coatings combined with vancomycin can eradicate bacteria on medical tubing, reducing antibiotic use and infection risk.

This study shows that a single delayed injection of recombinant human lubricin improves cartilage repair tissue quality and lubrication in a rabbit osteochondral defect model.

This paper develops high-specificity DNA aptamers for progesterone using a high-throughput array platform, achieving nanomolar affinity and minimal cross-reactivity with structurally similar steroids.

The paper develops a mathematical model to predict bone formation rate from Col1a1 gene expression data and compares it with literature-reported average BFR.

This paper develops a risk-aware control framework for insulin delivery that uses nonlinear MPC with safety barrier functions and probabilistic learning to manage glucose levels safely in diabetes management.

The paper demonstrates 2D nonlinear structured illumination microscopy (NSIM) using rsEGFP2 to achieve sub-80 nm resolution for live-cell actin imaging.

This study uses molecular modeling and simulation to analyze how different antifouling polymer brushes resist or modulate protein adsorption and structural dynamics.

This study compares stable isotope tracers and puromycin labeling in measuring muscle protein synthesis in engineered skeletal muscle, finding tracers detect anabolic responses missed by puromycin.

This study develops an integrated multi-analytical workflow to comprehensively profile biomass hydrolysate for downstream valorization.

This study uses chemical proteomics to profile cysteine reactivity in mAbs, revealing disulfide bond reduction mechanisms in CHO cell production.

This paper demonstrates that an intravenous lipid-siRNA conjugate can deliver gene silencing to brain barriers without affecting parenchymal tissue.

This study uses computational models to show how meniscus mechanics depend on microstructure and synovial fluid viscosity, finding that increased porosity significantly enhances flow velocity.

This paper improves the affinity and potency of a monoclonal antibody against Shigella flexneri 3a O-antigen using phage display and whole-cell panning, showing enhanced antibacterial activity and broader serotype recognition.

This paper develops a customized CRISPR-Cas9 base editor to correct the ACTA2 R179H mutation in a mouse model of MSMDS, improving survival and rescuing vascular and neurological phenotypes.

This study shows that platelet-derived biomaterials reduce mitochondrial dysfunction in neuronal injury models by restoring ATP production, reducing ROS, and improving mitochondrial structure and function.

The paper introduces a fibre-based structured illumination microscopy (SIM) system that simplifies setup and improves resolution without specialized optics.

This study shows that using a single plasmid for co-transfection is more efficient and results in tighter gene expression correlation than using multiple plasmids.

This study uses a mathematical model combined with OCTA images to simulate tumor-induced angiogenesis in retinal hemangioblastoma, revealing critical insights into the timing and dynamics of vascular development.