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Optimization of Functional Electric Stimulation for Foot Drop Patients using Inertial Measurement Unit.

This paper designs an online feedback control system using IMU data to optimize FES strength for drop foot patients, correcting pathological gait.

Neuronal Activity-Dependent Electroosmosis and Its Potential Role in Interstitial Fluid Flow in the Glymphatic System

This paper proposes electroosmosis as a mechanism for interstitial fluid flow in the brain, showing it generates realistic velocities and explains glymphatic transport differences between sleep and wakefulness.

Bayesian-enhanced closed-loop optimization of ultrasound protocols for targeted and precise neuromodulation

This paper develops BEACUN, a Bayesian-enhanced adaptive control method for optimizing LIFU neuromodulation protocols in rats, achieving faster convergence than conventional methods.

Adaptive Charge Modulation Enables Focal, Selective Spinal Cord Stimulation

This study introduces Adaptive Charge Modulation (ACM) for spinal cord stimulation, achieving focal activation at deep tissue sites with reduced surface activation and muscle co-activation.

Beyond mean trabecular separation: decomposing metaphyseal marrow space into local trabecular spacing and marrow cavity expansion

The paper decomposes trabecular separation into local trabecular spacing and marrow cavity expansion to better understand metaphyseal bone changes in osteoporosis, spinal cord injury, ovariectomy, and ageing.

Stage-adaptive integration of polydopamine promotes hPSC-derived alveolar organoids differentiation and maturation

This study shows that stage-adaptive integration of polydopamine coatings and nanoparticles enhances the maturation and secretory function of hPSC-derived alveolar organoids.

Mycoelectronics: Bioprinted Living Fungal Bioelectronics for Artificial Sensation

This paper introduces Mycoelectronics, a living fungal-based sensory platform that enables rapid thermal sensing and self-healing through bioprinted mycelium networks integrated with soft electronics.

Validation of a multiscale Hill-type actuator against comprehensive benchmarks of motor unit and muscle force measurements

This paper develops and validates a multiscale Hill-type neuromuscular actuator against experimental benchmarks of motor unit and muscle force measurements, showing improved accuracy in force reproduction.

Postnatal Pulmonary Artery Development from Transcript to Tissue

The paper presents data on normal postnatal development of pulmonary arteries in mice and develops a computational model to simulate responses to hemodynamic perturbations.

Cyclic stretch inhibits cell invasion in 3D scaffolds

This study shows cyclic stretch inhibits cell invasion in 3D scaffolds, with suppression inversely related to cell contractility.

Intra-nanoparticle Drug-protein Interactions Mediate Sequential Therapeutic Release

This study develops a drug delivery system using HSA nanoparticles where vancomycin modulates drug release kinetics through interactions with albumin's secondary structure.

Confidence-supported label-free metabolic imaging with FPhaS phase autofluorescence microscopy

This paper introduces FPhaS, a framework for confidence-supported label-free metabolic imaging using phase autofluorescence microscopy, improving accuracy by integrating structural and metabolic data.

Servo-Actuated 3D-Printed Disposable Microvalves for Automated, Scalable Organoid Culture in Standard Incubators

This paper develops a 3D-printed, servo-actuated microvalve system for automated organoid culture, validated in mouse and human models with comparable viability and gene expression to manual methods.

FALCON: Closed-Loop Multi-Objective Optimization of Lipid Nanoparticles for Cell-Selective mRNA Delivery

FALCON optimizes lipid nanoparticles for cell-selective mRNA delivery, improving transfection efficiency and selectivity in vivo.

Machine learning-guided olivetolic acid cyclase engineering enables tailored cannabinoid biosynthesis in yeast

This paper uses machine learning to engineer olivetolic acid cyclase in yeast, enhancing cannabinoid production and selectivity.

Microbubble Track-based Functional Ultrasound Localization Microscopy in Awake Mice

This paper develops a microbubble track-based method to improve functional ultrasound localization microscopy's sensitivity in awake mice without sacrificing spatial resolution.

Experiment-free learning of exoskeleton assistance is not an unsolved problem

The paper addresses criticisms of exoskeleton energy efficiency by analyzing published data, reviewing literature, and correcting methodological errors in a replication study, showing the problem is not unsolved.

Perivascular matrix densification dysregulates angiogenesis and activates pro-inflammatory endothelial cells

This study shows that perivascular matrix densification promotes fibrosis by activating pro-inflammatory endothelial cells through a novel VE-cadherin-TGF-βR2 axis.

Identification of Direct and Network-Mediated Activation of Retinal Ganglion Cells from Visually Evoked Potentials Using Machine Learning

The paper develops a machine learning model to identify retinal ganglion cell activation pathways from visually evoked potentials, avoiding the need for toxic synaptic blockers.

Nanomechanics of Mandible Wear in Insects

This study investigates the nanomechanical properties of insect mandibles, finding that wear resistance is not simply related to hardness or load, and suggesting limitations in current wear models.