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The paper identifies bacterial strains with plant growth-promoting and nematicidal traits that enhance tomato resistance to pathogens without fitness costs.

This study investigates how JAK2 modulates neutrophil function and how aging alters these mechanisms, revealing age- and sex-dependent changes in migration, NETosis, and metabolism.

This study shows that lymphatic dissemination through sequential lymph nodes is a major route for systemic spread of extracellular bacteria in soft tissue infections.

This study investigates how rapamycin modulates lymph node architecture, leukocyte trafficking, and gut microbiome over time, revealing a novel mechanism of immunosuppression.

This study uses cryo-EM to analyze antibodies against AAV9 vectors, identifying residues that enable capsid engineering to avoid neutralization and allow redosing.

This study shows that inducing TFEB in Kupffer cells reduces cell death, lipid accumulation, and inflammation in MASLD.

The paper uses single-cell RNA sequencing and flow cytometry to analyze ovarian immune cells in mice under high and low estradiol states, finding dynamic changes in NK and B cell populations during the periovulatory phase.

This study shows that IL-18 enhances antitumor activity of CAR-NKT cells against neuroblastoma by promoting metabolic reprogramming and reducing exhaustion markers.

This study shows that time-restricted feeding improves metabolic health in mice but has limited effect on reducing Mycobacterium tuberculosis burden early after infection.

The paper identifies Posaconazole as a CYP11A1 inhibitor that enhances anti-tumour immunity in a mouse model of lung metastasis.

This study shows that CXCL13 deficiency in mice worsens SARS-CoV-2 infection, with higher viral load, lung damage, and reduced B and T cell responses.

This study shows chronic BCR signaling generates and maintains age-associated B cells from anergic B cells, and Btk inhibition reduces ABCs and lupus pathogenicity.

This study uses ELISpot to assess immunomodulatory drug effects on cytokine production in sepsis patients and healthy controls.

This study shows that antigen avidity affects the durability and diversity of vaccine-induced immune responses by influencing germinal center dynamics and B cell outcomes.

This study identifies immune-related gene expression changes in asymptomatic Chagas cardiomyopathy patients, suggesting unique immune mechanisms in early disease progression.

The paper elucidates the cleavage cascade of FecR that mediates ferric citrate signaling via the TonB-FecA axis in Escherichia coli.

The paper shows that CD4 T cells can acquire TCR-independent IFN-gamma production capabilities through TCR and CD28 stimulation, suggesting a broader role in immune responses.

This study identifies pathogen-specific neutrophil surface protein phenotypes in bacterial pneumonia, revealing tissue- and infection-type dependent immune responses.

This study shows that pre-existing YFV-17D immunity reduces DENV-2 infection severity in mice through T cell cross-protection, not antibodies.

This paper develops a human lymphoid follicle chip platform to model intramuscular mRNA vaccine responses, showing it can replicate immune responses to both naive and recall antigens.