Caiying Guo

Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits

The paper introduces WHOLISTIC, a method to image cellular activity across all organs of a vertebrate, revealing body-wide circuits and responses to stimuli.

Magnetic voluntary head-fixation in transgenic rats enables lifetime imaging of hippocampal neurons

The paper introduces a magnetic voluntary head-fixation system for longitudinal imaging of hippocampal neurons in transgenic rats.

Spatiotemporal limits of optogenetic manipulations in cortical circuits

The paper benchmarks optogenetic silencers in mice to assess their spatial and temporal effects on cortical circuits, finding that photoinhibition extends beyond light spread and can produce paradoxical effects.

Dystroglycan is a scaffold for extracellular axon guidance decisions

This study identifies Dystroglycan as an extracellular scaffold that coordinates axon guidance by interacting with environmental cues and the receptor Celsr3/Adgrc3.

Thy1 transgenic mice expressing the red fluorescent calcium indicator jRGECO1a for neuronal population imaging in vivo

The paper presents transgenic mice expressing the red calcium indicator jRGECO1a for in vivo neuronal imaging, showing comparable or better signal-to-noise ratios than viral methods.

Knock-in rats expressing Cre and Flp recombinases at the Parvalbumin locus.

The paper generates and validates two knock-in rat strains expressing Cre or Flp recombinase under the Parvalbumin promoter for studying inhibitory interneurons.