Author

K. M. Ansel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 7

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3

Frequent Co-Authors

A. Marson· 2 shared D. M. Marquez· 2 shared I. Tenvooren· 2 shared J. D. Gagnon· 2 shared M. H. Spitzer· 2 shared M. S. Fassett· 2 shared A. I. Basbaum· 1 shared A. R. Atkins· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

A. Marson

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Author profile →

7 papers

Recent·Most cited

The lncRNA Malat1 Inhibits miR-15/16 to Enhance Cytotoxic T Cell Activation and Memory Cell Formation

B. D. Wheeler, J. D. Gagnon, W. S. Zhu, P. Munoz-Sandoval, S. K. Wong, D. S. Simeonov, Z. Li, R. Debarge, M. Spitzer, A. Marson, K. M. Ansel

This study identifies Malat1 as a regulator of miR-15/16 in cytotoxic T cells, showing that disrupting their interaction impairs T cell activation and memory formation.

bioRxiv · Apr 14, 2023 · PreprintImmunology

A conserved immune trajectory of recovery in hospitalized COVID-19 patients

T. L. H. Okholm, C. E. Burnett, I. Tenvooren, D. M. Marquez, S. Tamaki, P. M. Sandoval, The UCSF COMET Consortium, C. S. Calfee, C. M. Hendrickson, K. N. Kangelaris, C. R. Langelier, M. F. Krummel, P. G. Woodruff, D. J. Erle, K. M. Ansel, M. H. Spitzer

The paper identifies a conserved immune recovery trajectory in hospitalized COVID-19 patients through longitudinal mass cytometry analysis, linking immune processes to clinical outcomes.

bioRxiv · Mar 15, 2022 · PreprintImmunology

IL-31 uncouples skin inflammation from itch sensation in allergic dermatitis

M. S. Fassett, J. M. Braz, C. A. Castellanos, A. W. Schroeder, M. Sadeghi, D. J. Mar, C. J. Zhou, J.-S. Shin, A. I. Basbaum, K. M. Ansel

This study shows IL-31 limits allergic skin inflammation but is essential for itch sensation in dermatitis, uncoupling inflammation from itch.

bioRxiv · May 12, 2021 · PreprintImmunology

Type 2 innate immunity regulates hair follicle homeostasis to control Demodex pathosymbionts

R. R. Ricardo-Gonzalez, M. E. Kotas, I. Tenvooren, D. M. Marquez, M. S. Fassett, J. Lee, S. G. Daniel, K. Bittinger, R. E. Diaz, J. S. Fraser, K. M. Ansel, M. H. Spitzer, H.-E. Liang, R. M. Locksley

This study shows that type 2 innate immunity, via ILC2s, regulates hair follicle homeostasis and maintains commensal Demodex mite colonization.

bioRxiv · Mar 29, 2021 · PreprintImmunology

The non-coding RNA miR-17~92 is a central mediator of T cell activation

M. Doelz, J. D. Gagnon, M. Kornete, R. Marone, G. Bantug, R. Kageyama, C. Hess, K. M. Ansel, D. Seyres, J. Roux, L. T. Jeker

This study identifies miR-17~92 as a central mediator of T cell activation by enhancing the calcineurin/NFAT pathway and repressing negative regulators of activation.

bioRxiv · Oct 13, 2020Immunology

Obesity Potentiates TH2 Immunopathology via Dysregulation of PPAR

S. Bapat, Y. Liang, S. Liu, L.-j. Zhang, I. Vogel, D. J. Marr, C. Zhou, E. J. Choi, C. Chang, N. He, M. LeBlanc, I.-k. Lee, J. M. Suh, L. E. Crotty Alexander, C. Liddle, , Y. Zheng

This study shows obesity increases TH2 immunopathology by disrupting PPARγ in T cells, and TZDs can protect against this effect in obese mice.

bioRxiv · Oct 31, 2019 · PreprintImmunology

Profiling immunoglobulin repertoires across multiple human tissues by RNA Sequencing

S. Mangul, I. Mandric, H. T. Yang, N. Strauli, D. Montoya, J. Rotman, W. V. Der Wey, J. R. Ronas, B. Statz, A. Zelikovsky, R. Spreafico, S. Shifman, N. Zaitlen, M. Rossetti, K. M. Ansel, E. Eskin

The paper develops ImReP, a computational method to profile TCR and BCR repertoires from RNA-seq data, creating a large atlas of immunological sequences across 53 tissues.

bioRxiv · Nov 6, 2018 · PreprintImmunology