Author
H. Xia
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2018-2024 · peak 15/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links36 papers
Recent·Most cited
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single moleculeperspective
M. Seifert, S. C. Bera, P. van Nies, R. N. Kirchdoerfer, A. Shannon, T.-T.-N. Le, X. Meng, H. Xia, J. M. Wood, L. D. Harris, F. S. Papini, J. J. Arnold, S. C. Almo, T. L. Grove, P.-Y. Shi, , D. Dulin
This study investigates how nucleotide analogs like Remdesivir affect SARS-CoV-2 polymerase activity using single-molecule techniques, revealing backtracking rather than termination and evasion of ddhCTP.
bioRxiv · Aug 6, 2020 · PreprintBiophysics
Morning glory species co-occurrence is associated with asymmetrically decreased and cascading reproductive isolation
K. L. Ostevik, J. L. Rifkin, H. Xia, M. D. Rausher
The paper investigates how asymmetric gene flow between morning glory species affects reproductive barrier strength, finding that introgression decreases barriers in the recipient species and impacts within-species compatibility.
bioRxiv · Jun 10, 2020Evolutionary Biology
The conservation of a core virome in Aedes mosquitoes across different developmental stages and continents
C. Shi, L. Zhao, W. Zeng, E. Atoni, X. Hu, J. Matthijnssens, Z. Yuan, H. Xia
This study identifies a vertically transmitted core virome in Aedes albopictus mosquitoes across developmental stages and continents, and finds a novel virus related to Yongsan bunyavirus 1.
bioRxiv · Apr 23, 2020 · PreprintMicrobiology
The characterization of a humanized rabbit anti-TNF α monoclonal antibody?A nationwide RA treatment drug study
c. wang, x. Ni, y. Liu, z. Jin, h. Xia, N/A
This study develops a rabbit-derived anti-TNFα monoclonal antibody (HZ3M) showing improved neutralizing activity and longer half-life compared to existing therapies like Humira.
bioRxiv · Dec 18, 2019 · PreprintCell Biology
The Dimer-dependent Catalytic Activity of RAF Family Kinases Is Revealed Through Characterizing Their Oncogenic Mutants
J. Yuan, W. H. Ng, P. Y. P. Lam, Y. Wang, H. Xia, J. Yap, S. P. Guan, A. S. G. Lee, M. Wang, M. Baccarini, J. Hu
This study identifies dimer-dependent catalytic activity in RAF family kinases through analysis of oncogenic mutants, revealing differential inhibitor resistance and MEK phosphorylation mechanisms.
bioRxiv · Jun 4, 2018Cancer Biology