K. Fukunaga

Memory B cells and memory T cells induced by SARS-CoV-2 booster vaccination or infection show different dynamics and efficacy to the Omicron variant.

Fc-modified SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.

The paper develops Fc-modified SARS-CoV-2 neutralizing antibodies effective against variants, showing reduced viral titers and lung damage in animal models.

Epsin2, a novel target for multiple system atrophy therapy via α-synuclein/FABP7 propagation

This study identifies epsin-2 as a therapeutic target for multiple system atrophy by regulating FABP7/-synuclein hetero-aggregates propagation.

Quantitative live-cell imaging of secretion activity reveals dynamic immune responses

This paper introduces qLCI-S, a method for quantitative live-cell imaging of secretion activity, enabling single-cell analysis of cytokine secretion and transcriptome profiling of rare cell populations.

Nasal delivery of single-domain antibodies improve symptoms of SARS-CoV-2 infection in an animal model

This paper shows nasal delivery of a camelid single-domain antibody reduces SARS-CoV-2 titers in hamsters without weight loss or cytokine induction.

Relationship between ocean area and incidence of anthropogenic debris ingested by longnose lancetfish (Alepisaurus ferox)

This study examines plastic ingestion in longnose lancetfish across different ocean areas, finding higher incidence in Sagami Bay compared to the North Pacific and Indian Ocean.

Laminin heparin-binding peptides promiscuously bind growth factors and enhance diabetic wound healing

This study shows laminin heparin-binding peptides bind growth factors and enhance diabetic wound healing by acting as GF reservoirs and cell scaffolds.