Author

K. J. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. Y. Lee· 2 shared A. Louie· 1 shared D. A. Portnoy· 1 shared D. I. Kotov· 1 shared D. S. Zamboni· 1 shared D. X. Ji· 1 shared H. Bateup· 1 shared H. L. Reesink· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. Y. Lee

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Recombinant manufacturing of multispecies biolubricants

M. J. Colville, L.-T. Huang, S. Schmidt, K. J. Chen, K. Vishwanath, J. Su, R. Williams, L. Bonassar, H. L. Reesink, M. J. Paszek

This study develops recombinant lubricin analogs with improved biocompatibility and lubricating properties, demonstrating their tissue binding and joint retention in rats.

bioRxiv · May 5, 2024 · PreprintBioengineering

Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons

D. X. Ji, K. C. Witt, D. I. Kotov, S. R. Margolis, A. Louie, V. Chevee, K. J. Chen, M. Gaidt, H. S. Dhaliwal, A. Y. Lee, S. Nishimura, D. S. Zamboni, I. Kramnik, D. A. Portnoy, K. H. Darwin, R. E. Vance

This study identifies SP140 as a repressor of type I interferons that enhances resistance to bacterial infections like Legionella pneumophila and Mycobacterium tuberculosis.

bioRxiv · Jan 7, 2020Immunology

STING controls Herpes Simplex Virus in vivo independent of type I interferon induction

L. H. Yamashiro, S. C. Wilson, H. M. Morrison, V. Karalis, J.-Y. J. Chung, K. J. Chen, H. Bateup, M. L. Szpara, A. Y. Lee, J. S. Cox, R. Vance

This study shows that STING controls HSV-1 infection independently of type I interferon induction, through autophagy and other ancestral functions.

bioRxiv · Dec 12, 2019 · PreprintImmunology