Q. Wang

This study shows GSTZ1 enhances sorafenib-induced ferroptosis in HCC by inhibiting the NRF2/GPX4 axis, and its deficiency leads to resistance to sorafenib.

The paper develops a method to trace the geographic origin of quarantine insects using their gut microbiota, finding that microbiota diversity and composition correlate with geographic and environmental factors.

This study shows ORMDL1 is upregulated in colorectal cancer and associated with better patient survival.

This paper develops data-informed strategies to design hydrolytic nanozymes with enhanced catalytic activity and broad substrate specificity.

This study identifies abundant and diverse circRNAs from SARS-CoV-2, SARS-CoV, and MERS-CoV, revealing a novel type of circRNA distinct from DNA-encoded circRNAs.

This study shows that calorie restriction affects gut microbiome, which in turn influences metabolism, hormones, and brain function in obese individuals.

This study examines how different light spectra affect nitrogen assimilation and content in Quercus variabilis seedlings under nitrogen pulses.

This paper demonstrates that hydrogel-coating enhances the in vivo stability of electrochemical aptamer-based biosensors without compromising detection performance.

This paper reports a monoclonal antibody, 3E8, that blocks multiple coronaviruses by targeting ACE2, showing broad-spectrum activity against SARS-CoV-2 variants and other coronaviruses.

This study identifies LsAP2 as a transcription factor regulating seed shape in lettuce, showing its role in seed development and dispersal through interactions with LsBP and involvement in brassinosteroid pathways.

This paper optimizes a baculovirus system to efficiently produce all rAAV serotypes 1-13, achieving high yields and scalability for research and therapeutic applications.

The paper reports cryo-EM structures of SARS-CoV-2 RdRp with nucleoside inhibitors, revealing their mechanism and guiding the design of more potent derivatives.

This study identifies key features of the SARS-CoV-2 spike glycoprotein, including the furin cleavage site and D614G mutation, that influence viral infectivity, stability, and cytopathicity.

The paper investigates cross-reactivity between mugwort and house dust mite allergens, finding that mugwort tropomyosin induces a non-Th2 response in allergic rhinitis patients.

The paper develops a method to delete large genomic regions in Nannochloropsis oceanica, showing that non-essential regions can be removed without affecting key traits.

The paper shows human chromosomes randomly distribute to neutrophil nuclear lobes but maintain non-random radial organization within lobes, revealing new insights into chromosome territory dynamics.

This paper proposes a gait-symmetry-based human-in-the-loop optimization method for unilateral transtibial amputees, improving gait symmetry and reducing metabolic cost.

This study shows that epithelial HVEM supports basement membrane synthesis and IET survival and migration in the intestine.

This study evaluates two adenovirus vectored COVID-19 vaccines in mice and macaques, showing strong immune responses after prime-boost vaccination.

This study identifies CARD8 as a sensor of HIV-1 protease activity, triggering pyroptosis of infected cells and clearing latent HIV-1 in CD4+ T cells.

This study finds that patients with severe SARS-CoV-2 disease have higher antibody titers against viral proteins and neutralization capabilities compared to less severe cases.

This study shows that combining free ammonia pretreatment with anaerobic digestion reduces antibiotic resistance gene abundances in sludge.

This study uses micro-XRF to analyze the holotype of Jianianhualong tengi, revealing elemental patterns linked to fossil structure and taphonomy.

This study shows that inhibiting GMPS reduces glutamine metabolism and prostate cancer growth in vitro and in vivo.

This study compares the receptor utilization of SARS-CoV and SARS-CoV-2 using ACE2s from 20 animals, finding SARS-CoV-2 uses fewer ACE2s, suggesting a narrower host range.

This paper investigates how Na+ flux through DISP1 enables release of lipid-modified Hedgehog signals by analyzing structural and functional changes in DISP1 variants.

The paper uses single-molecule techniques to show catalysis does not enhance diffusion of alkaline phosphatase, contradicting previous FCS results attributed to substrate-induced dye blinking.

The paper identifies public antibody clones in the human repertoire, including virus-neutralizing and anti-PD1 clones, and introduces a tool for analyzing Rep-seq data.