Author

T. Xiang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Microbiology· 2 Bioengineering· 1 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Organism:mouse· 2

Frequent Co-Authors

H. Wang· 2 shared J. Huang· 2 shared J. Liu· 2 shared L. Wang· 2 shared q. Huang· 2 shared X. Wang· 2 shared x. Wu· 2 shared A. Le· 1 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersMicrobiology

H. Wang

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Distribution, Prevalence of Non-Tuberculous Mycobacteria in Hainan Island and Antibiotic Resistance of Mycobacterium abscessus

X. Xu, J. Huang, H. Wang, T. Xiang, J. Liu, L. Zheng

This study maps NTM distribution and antibiotic resistance in Hainan Island, identifying key species and resistance patterns to inform regional surveillance and treatment.

bioRxiv · Jun 9, 2024Microbiology

Dehydrozaluzanin C- derivative protects septic mice by alleviating over-activated inflammatory response and promoting the phagocytosis of macrophages

y. Zou, t. Xiang, l. Xu, h. Zhang, y. Ma, l. Zhang, c. Zhou, x. Wu, q. Huang, b. Lei, j. Mu, X. Qin, X. Jiang, y. Zheng

DHZD reduces inflammation and enhances macrophage phagocytosis in septic mice, showing potential as an HDT agent for bacterial infections.

International Immunopharmacology · May 1, 2024Peer-reviewedPharmacology & Toxicology

Redistribution and activation of CD16brightCD56dim NK cell subset to fight against Omicron subvariant BA.2 after COVID-19 vaccination

Y. Liu, H. Peng, T. Xiang, F. Xu, Y. Jiang, L. Zhong, Y. Peng, A. Le, W. Zhang

This study shows that COVID-19 vaccination enhances the activation and redistribution of CD16brightCD56dim NK cells in Omicron BA.2-infected patients, improving clinical outcomes.

bioRxiv · Jan 13, 2023 · PreprintImmunology

Shell Microelectrode Arrays (MEAs) for brain organoids

Q. Huang, B. Tang, J. C. Romero, Y. Yang, S. K. Elsayed, G. Pahapale, T.-J. Lee, I. E. M. Pantoja, F. Han, C. Berlinicke, T. Xiang, M. Solazzo, T. Hartung, Z. Qin, B. Caffo, , D. H. Gracias

This paper develops shell microelectrode arrays (MEAs) for brain organoids, enabling long-term electrophysiology recording from 3D organoids.

bioRxiv · Apr 13, 2022Bioengineering

Pparg drives luminal differentiation and luminal tumor formation in the urothelium

T. Tate, T. Xiang, M. Zhou, W. Y. Kim, X. Chen, H. Kim, E. Batourina, C.-S. Lin, C. Lu, S. E. Wobker, J. M. Mckiernan, C. L. Mendelsohn

This study shows that Pparg promotes luminal differentiation and tumor formation in urothelial cells, with tumors showing immune desertion and potential subtype shifts over time.

Nature Communications · Oct 25, 2021Peer-reviewedCancer Biology

Identification of green lineage osmotic stress pathways

J. Vilarrasa-Blasi, T. Vellosillo, R. E. Jinkerson, F. Fauser, T. Xiang, B. B. Minkoff, L. Wang, K. Kniazev, M. Guzman, J. Osaki, M. R. Sussman, M. C. Jonikas, J. R. Dinneny

This study identifies conserved osmotic stress pathways in green algae and plants using transcriptomics and functional genomics, revealing a novel actin remodeling mechanism.

bioRxiv · Jul 19, 2021 · PreprintPlant Biology

Occurrence of COVID-19 symptoms during SARS-CoV-2 infection defines waning of humoral immunity

J. Wu, B. Liang, Y. Fang, H. Wang, X. Yang, S. Shen, L. Chen, S. Li, S. Lu, T. Xiang, J. Liu, V. T. K. Le-Trilling, M. Lu, D. Yang, F. Deng, , X. Zheng

The study compares antibody responses in asymptomatic and symptomatic SARS-CoV-2感染者, finding that symptomatic individuals maintain higher and longer-lasting IgG and neutralizing capacities.

bioRxiv · Mar 26, 2021Immunology

MAPK Pathway Inhibition as A Rational Therapeutic Strategy for MiR-138-5p/PAQR3 Dysregulation-mediated Epirubicin Resistance in Triple-negative Breast Cancer

J. Huang, Y. Xiao, S. Zeng, X. Wang, H. Li, T. Xiang, L. Kong, G. Ren

This study identifies PAQR3 as a predictor of epirubicin response in TNBC and shows that MAPK inhibition can reverse resistance caused by miR-138-5p-mediated PAQR3 downregulation.

bioRxiv · Feb 28, 2021 · PreprintCancer Biology

Gut microbiome couples gut and brain during calorie restriction in treating obesity

Q. Zeng, Q. Wang, T. Xiang, L. Ou, X. Wu, K. Cai, C. Geng, M. Han, Z. Li, Z. Li, W. Wang, T. Yang, F. Li, H. Ma, X. Zhao, , J. Wang

This study shows that calorie restriction affects gut microbiome, which in turn influences metabolism, hormones, and brain function in obese individuals.

bioRxiv · Dec 4, 2020 · PreprintMicrobiology