Author

S. A. Oakes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Mohamed· 2 shared C. Dann· 2 shared D. Silva· 2 shared D. Yang· 2 shared G. Randall· 2 shared H. Gula· 2 shared L. C. Nguyen· 2 shared M. R. Rosner· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. Mohamed

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inhibition of the Eukaryotic Initiation Factor-2-α Kinase PERK Decreases Risk of Autoimmune Diabetes in Mice

C. Muralidharan, F. Huang, J. R. Enriquez, J. E. Wang, J. B. Nelson, T. Nargis, S. C. May, A. Chakraborty, K. T. Figatner, S. Navitskaya, C. M. Anderson, V. Calvo, D. Surguladze, M. J. Mulvihill, X. Yi, , R. G. Mirmira

This study shows that inhibiting PERK reduces autoimmune diabetes risk in mice by decreasing β cell immunogenicity and improving islet function.

bioRxiv · Oct 6, 2023Cell Biology

SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1α/XBP1 ER stress pathway in human lung-derived cells

L. C. Nguyen, D. M. Renner, D. Silva, D. Yang, N. Parenti, K. M. Medina, V. Nicolaescu, H. Gula, N. Drayman, A. Valdespino, A. Mohamed, C. Dann, K. Wannemo, L. Robinson-Mailman, A. Gonzalez, , S. R. Weiss

This study compares how SARS-CoV-2 and other betacoronaviruses activate the IRE1α/XBP1 ER stress pathway in human lung cells, finding that SARS-CoV-2 only partially activates it, potentially evading host immune detection.

bioRxiv · Dec 30, 2021 · PreprintMicrobiology

Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response

L. C. Nguyen, D. Yang, V. Nicolaescu, T. Best, S. Chen, J. B. Friesen, N. Drayman, A. Mohamed, C. Dann, D. Silva, H. Gula, K. A. Jones, J. M. Millis, B. C. Dickinson, S. Tay, , M. R. Rosner

This study shows that cannabidiol inhibits SARS-CoV-2 replication and enhances the host innate immune response in lung cells and human patients.

bioRxiv · Mar 10, 2021 · PreprintMicrobiology

Parallel signaling through IRE1α and PERK regulates pancreatic neuroendocrine tumor growth and survival

P. C. Moore, J. Y. Qi, M. Thamsen, R. Ghosh, J. Peng, M. J. Gliedt, R. Meza-Acevedo, R. E. Warren, A. Hiniker, G. E. Kim, D. J. Maly, B. J. Backes, F. R. Papa, S. A. Oakes

This study shows that targeting the UPR components IRE1α and PERK can inhibit pancreatic neuroendocrine tumor growth by inducing apoptosis through reciprocal signaling.

bioRxiv · Sep 18, 2019Cancer Biology