Author

W. Tao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Cell Biology· 3 Biophysics· 2 Cancer Biology· 2 Plant Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 11 Research Focus:cell type annotation· 7 Organism:mouse· 6 Approach:statistical model· 6 Organism:human· 5 Assay:bulk RNA-seq· 4 Research Focus:chromatin & epigenetic regulation· 4 Research Focus:gene regulatory network inference· 4

Frequent Co-Authors

J. Wang· 4 shared L. Zhang· 3 shared X. Chen· 3 shared C. Kuang· 2 shared C. Zhang· 2 shared D. Wang· 2 shared L. Xu· 2 shared W. Li· 2 shared

Activity by Year

2019-2023 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

J. Wang

Mutual co-authors in cluster

Author profile →

16 papers

Recent·Most cited

Application of slow-controlled release fertilizer coordinates the carbon flow in carbon-nitrogen metabolism to effect rice quality

Z. Jiang, Q. Chen, D. Liu, W. Tao, S. Gao, J. Li, C. Lin, M. Zhu, Y. Ding, W. Li, G. Li, S. Sakr, L. Xue

This study evaluates five slow-controlled release fertilizers on rice quality over two years, finding that BBF improves yield and grain quality by optimizing carbon-nitrogen metabolism.

bioRxiv · Dec 7, 2023Plant Biology

Multi-color live-cell optical nanoscopy using phasor analysis

Z. Zhang, Y. Huang, W. Tao, Y. Wei, L. Xu, W. Gong, Y. Zhang, Y. Han, C. Kuang, X. Liu

This paper introduces a method to enable multicolor live-cell STED imaging with at least 4 colors using phasor analysis to separate dyes of the same spectrum.

bioRxiv · Aug 4, 2023 · PreprintCell Biology

Histone lactylation antagonizes senescence and skeletal muscle aging via facilitating gene expression reprogramming

X. Zhang, F. Meng, W. Lyu, J. He, R. Wei, Z. Du, C. Zhang, Y. Guan, X. Huang, G. Lyu, X.-L. Tian, L. Zhang, W. Tao

This study shows histone lactylation counteracts senescence and skeletal muscle aging by reprogramming gene expression, with exercise enhancing lactylation and improving muscle function.

bioRxiv · May 26, 2023 · PreprintCell Biology

Optimization of 3-Cyano-7-cyclopropylamino-pyrazolopyrimidines Toward the Development of an In Vivo Chemical Probe for CSNK2

X. Yang, H. W. Ong, R. J. Dickmander, J. L. Smith, J. W. Brown, W. Tao, E. Chang, N. J. Moorman, A. D. Axtman, T. M. Willson

The paper develops analogs of SGC-CK2-1 to improve pharmacokinetic properties in mice by inhibiting GST and P450 enzymes through co-dosing protocols.

bioRxiv · May 15, 2023Pharmacology & Toxicology

The soluble guanylyl cyclase pathway is inhibited to evade androgen deprivation-induced senescence and enable progression to castration resistance

P. Rai, L. Zhang, C. I. Troccoli, B. Mateo-Victoriano, L. Misiara, E. N. Jackson, P. Shu, T. M. Plastini, W. Tao, D. Kwon, X. Chen, J. Sharma, M. Jorda, J. L. Gulley, M. Bilusic, , A. Beuve

This study identifies the soluble guanylyl cyclase (sGC) pathway as a target for castration-resistant prostate cancer (CRPC) treatment, showing that riociguat inhibits CRPC growth and enhances radiation response.

bioRxiv · May 3, 2023 · PreprintCancer Biology

Insm1 regulates the development of mTECs and immune tolerance

W. Tao, Y. Wei, Z. Ye, J. Wang, W. Yang, G. Yu, J. Xiong, S. Jia

This study shows that Insm1 regulates mTEC development and immune tolerance by interacting with Aire and affecting gene expression.

bioRxiv · Jan 14, 2023Immunology

Accurate background reduction in adaptive optical 3D-STED nanoscopy by dynamic phase switching

S. Tu, X. Liu, D. Yuan, W. Tao, Y. Han, Y. Shi, Y. Li, C. Kuang, X. Liu, Y. Yao, Y. Xu, X. Hao

This paper introduces a method to improve signal-to-background ratio in 3D-STED nanoscopy using dynamic phase switching with adaptive optics.

bioRxiv · Jun 25, 2022 · PreprintBiophysics

Enhanced competitive protein exchange at the nano-bio interface enables ultra-deep coverage of the human plasma proteome

D. Hornburg, S. Ferdosi, M. Hasan, B. Tangeysh, T. R. Brown, T. Wang, E. M. Elgierari, X. Zhao, A. Alavi, J. Chu, M. Figa, W. Tao, J. Wang, M. Goldberg, H. Xia, , O. C. Farokhzad

The paper develops a method using engineered nanoparticles to enhance plasma proteome coverage by optimizing protein-NP interactions and competition, resulting in deeper and more consistent proteomic profiling.

bioRxiv · Jan 8, 2022 · PreprintBiophysics

AMPK mediates early activation of the unfolded protein response through a positive feedback loop in palmitate-treated muscle cells

J. Gong, L. Wang, W. Tao, Z. Liu, W. Li, Y. Liu, X. Chen, P. Zhang

This study shows AMPK and UPR interact via a positive feedback loop in muscle cells exposed to palmitate, with AMPK agonists enhancing UPR gene expression.

bioRxiv · Oct 12, 2021Physiology

m6A modifications regulate intestinal immunity and rotavirus infection

S. Zhu, A. Wang, J. Wang, W. Tao, S. Ding, R. A. Flavell, J. Tong, G. Hou, J. Gao, G. Zhang, R. Li, X. Ren, D. Wang, K. Zhang, W. Pan, , C. Qian

This study shows that m6A modifications regulate intestinal immunity and rotavirus infection by modulating IRF7 and IFN expression through METTL3 in intestinal epithelial cells.

bioRxiv · Sep 17, 2021Immunology

HAUSP Stabilizes SOX2 through Deubiquitination to Maintain Self-renewal and Tumorigenic Potential of Glioma Stem Cells

Z. Huang, K. Zhai, Q. Wu, X. Fang, Q. Huang, W. Tao, J. D. Lathia, J. S. Yu, J. N. Rich, S. Bao

This study identifies HAUSP as a deubiquitinase that stabilizes SOX2 in glioma stem cells, maintaining their self-renewal and tumorigenic potential, and shows that targeting HAUSP can enhance GBM treatment.

bioRxiv · Jun 9, 2021 · PreprintCancer Biology

ATF3 drives senescence by reconstructing accessible chromatin profiles

C. Zhang, X. Zhang, Y. Guan, X. Huang, L. Zhang, X.-L. Tian, W. Tao

The paper identifies ATF3 as a key driver of chromatin accessibility remodeling during senescence, linking it to the regulation of senescence programs.

Aging Cell · Feb 4, 2021Peer-reviewedCell Biology

Conserved human effector Treg signature is reflected in transcriptomic and epigenetic landscape

G. Mijnheer, L. Lutter, M. Mokry, M. van der Wal, V. Fleskens, R. Scholman, A. Pandit, W. Tao, M. Wekking, S. Vervoort, C. Roberts, A. Petrelli, J. Peeters, M. Knijff, S. de Roock, , F. van Wijk

The paper identifies a conserved human effector Treg signature through transcriptomic and epigenetic analysis, showing overlap with tumor-infiltrating Treg and environment-driven adaptations.

bioRxiv · Sep 30, 2020 · PreprintImmunology

Evolution of a sex megachromosome

M. A. Conte, F. B. Clark, R. B. Roberts, L. Xu, W. Tao, Q. Zhou, D. Wang, T. D. Kocher

The paper investigates the evolution of a sex megachromosome in cichlid fish, finding it consists of three distinct regions and contains unique genomic features.

bioRxiv · Jul 2, 2020 · PreprintEvolutionary Biology

Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Endosomal Sensing by Dendritic Cells in Psoriasis

F. Lou, Y. Sun, Z. Xu, L. Niu, Z. Wang, S. Deng, Z. Liu, H. Zhou, J. Bai, Q. Yin, X. Cai, L. Sun, H. Wang, Z. Wu, X. Chen, , H. Wang

This study shows that excessive polyamine production in keratinocytes drives self-RNA sensing by dendritic cells, contributing to psoriasis inflammation.

bioRxiv · Mar 9, 2020Immunology

PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development in Arabidopsis thaliana

F. ZHANG, W. Tao, R. Sun, J. Wang, C. Li, X. Kong, H. Tian, Z. Ding

This study identifies PRH1 as a target of ARF7 and LBDs in auxin signaling, showing its role in lateral root development through interaction with GATA23.

bioRxiv · Feb 22, 2019Plant Biology