S. Xu

This study identifies a comprehensive atlas of B-lymphocytes in triple-negative breast cancer using single-cell RNA-sequencing and antigen receptor profiling, revealing their mature characteristics and prognostic significance.

This study conducts a meta-analysis showing opioids increase fracture risk by 78% in patients with chronic noncancer pain.

The paper identifies a novel plant-specific TRAPP complex component, TRIPP, and shows its role in plant development through proteomic and genetic analyses in Arabidopsis.

The paper analyzes gene panel sequencing data from 829 Chinese high-risk breast cancer patients to identify pathogenic variants and variants of uncertain significance across 115 hereditary cancer susceptibility genes.

This study evolves E. coli under acid stress and identifies genetic and expression changes that enhance acid tolerance.

This study uses TurboID to identify protein interactions and cell type-specific organellar proteomes in Arabidopsis, revealing novel interactors of a transcription factor and subcellular proteomes.

This study examines the evolution of the glutathione S-transferase gene family in cetaceans, finding lineage-specific gene losses and positive selection, suggesting adaptation to aquatic environments.

This paper investigates how Prototheca zopfii genotype II causes mitochondrial apoptosis and inflammation in bovine mastitis models.

This study identifies and characterizes a novel pic gene cluster in Alcaligenes faecalis JQ135 responsible for complete picolinic acid degradation into the tricarboxylic acid cycle.

This study identifies E-cadherin's role in suppressing sarcoma growth through both signaling (inhibiting p-CREB and TBX2) and mechanical (enhancing cell-cell adhesion) mechanisms.

This paper uses NMR to determine how P[8] and P[6] rotavirus VP8* domains bind to different histo-blood group antigens, revealing structural differences that may explain their distinct host ranges and evolutionary adaptations.

This study identifies Alexidine dihydrochloride as a broad-spectrum antifungal drug effective against multiple fungal pathogens and preformed biofilms.

This paper confirms Methanosarcina barkeri can uptake electrons from cathodes, linking it to increased methane production and identifying both hydrogenase-mediated and hydrogenase-independent pathways for cathodic electron uptake.

This paper introduces a tumor-specific causal inference framework to identify causative somatic genome alterations and their impact on molecular phenotypes in individual tumors.

This paper describes the fusion of DN and AflR genes to create a novel protein that enhances anti-A. flavus activity compared to DN alone.

The paper improves rice genome annotation by analyzing RNA-Seq and proteomics data, identifying 692 genomic loci with potential annotation updates.

This paper demonstrates the use of polymer dots for deep in vivo multiphoton imaging in mice, showing improved signal-to-background ratio and imaging depth.

The paper determines the structure of pro-TGF-β1 with a cleavage site mutation, revealing prodomain-GF domain swapping in the dimeric structure and its implications for TGF-β biosynthesis.

This study introduces iMAAPs, a method to infer multiple-wave population admixture by modeling ALD decay with polynomial functions, showing improved performance over existing methods.