T. Zhao

The paper investigates the subcellular localization of Psd1 and shows that impaired phosphatidylethanolamine metabolism triggers an ER-assisted response to resolve nonfunctional mitochondrial precursors.

This study compares the temporal transcriptomes of two Verticillium dahliae strains to identify pectin degradation genes linked to pathogenicity in Upland cotton.

This study identifies CATP-8 as an ER-localized P5A ATPase that removes mislocalized mitochondrial proteins from the ER, preserving ER identity and function.

The paper develops deep learning models using RNA-seq data that incorporate isoform and exon information to improve smoking status prediction, achieving higher AUC than gene-level models.

This study shows that JNK1/2 phosphorylates BNIP3 under hypoxia, enhancing its stability and promoting mitophagy by increasing its binding to LC3.

The paper identifies 319 compounds with anti-SARS-CoV-2 activities through a high-throughput screen, including 91 approved drugs and 49 investigational drugs, with 230 compounds previously unreported.

This study examines the interannual variability of net ecosystem carbon production in a rain-fed maize ecosystem, identifying climatic and biotic factors influencing carbon dynamics from 2005 to 2018.

This study identifies an IL1β/NFκB/ESE3 signaling axis in pancreatic stellate cells that drives fibrosis, chemoresistance, and poor prognosis in pancreatic cancer.

This study investigates how microplastics and drought interact to affect ecosystem functions and multifunctionality in grassland soils.

This paper describes the NCATS OpenData Portal, a platform for real-time sharing of drug screening data that accelerates translational research by enabling immediate access to large-scale datasets.

This study uses iPSC-derived cardiomyocytes from DCMA patients to show reversible mitochondrial fragmentation and OPA1 isoform imbalance, suggesting SS-31 as a potential therapy.

This study identifies Cqs2 as the critical determinant for orchestrating the unisexual cycle in Cryptococcus neoformans without requiring the sex-determination program.

This study uses super-resolution imaging to show that E. coli SSB relocates from the inner membrane to the cell interior in response to DNA damage, forming foci for repair.

This study shows that SS-31 reverses mitochondrial fragmentation and increases ROS in DCMA fibroblasts, suggesting it as a potential therapy for this mitochondrial cardiomyopathy.

This study sequenced the genome of Castanospermum australe, a desiccation-sensitive legume, and found that its seeds remain metabolically active and lack mechanisms for desiccation tolerance.

This study combines Azospirillum brasilense inoculation with seed priming to enhance germination and seedling growth in aged grass seeds, finding that H2O2 priming with optimal bacterial concentration and time is most effective.

This study identifies ANRIL as a key lncRNA promoting HTLV-1-induced ATL cell proliferation through interaction with EZH2 and activation of NF-κB.

The paper constructs microsynteny networks for mammalian and angiosperm genomes to compare synteny conservation and diversification across these lineages.

The paper identifies a novel viral mechanism that hijacks the nucleolar DNA-damage response pathway by interacting with Treacle to inhibit rRNA biogenesis.