X. Shi

This study identifies stem cell-like GBM cells outside the contrast-enhancing region and proliferative lymphocytes in GBM patients' blood, linking them to recurrence and immunotherapy.

The paper shows that two forms of Opa1 work together to regulate mitochondrial inner-membrane fusion, with l-Opa1 enabling docking and s-Opa1 facilitating efficient pore opening.

The paper shows that nanotopography induces dynamic changes in tight junction proteins by forming cytosolic complexes that regulate paracellular permeability.

This study identifies small molecules that induce cellular stress resistance against paraquat, cadmium, and methyl methanesulfonate, with some compounds activating Nrf2 signaling and others triggering inflammatory and AMPK pathways.

The paper identifies CREBBP dependency in a DLBCL cell line with EP300 truncation using CRISPR-Cas9 screens and genomic data, suggesting therapeutic targets for heterogeneous cancers.

This study evaluates the methodological quality of animal studies using the SYRCLEs risk of bias tool, finding significant differences between Chinese and English studies.

This study tracks the development of a potent ZIKV-specific antibody in a convalescent human, revealing limited somatic hypermutation and high germline identity.

The paper introduces a presuppositionless method to analyze single nanoparticle trajectories by leveraging their historical data, revealing spatiotemporal patterns without predefined models.

The study identifies a mutant birch tree (Elimaki) with impaired proprioception and radial growth, linking mechanical stress response to cell wall properties and transcriptomic changes.

This study identifies extensive horizontal gene transfer from bacterial origins in the genome of the fungal pathogen Verticillium dahliae.

This study predicts and characterizes secondary metabolite clusters in Verticillium dahliae to uncover its potential secondary metabolites.

The paper develops a method to align semi-flexible 3D structures from super-resolution microscopy images with high accuracy and efficiency, demonstrating it on STORM images of ciliary distal appendages.

The paper demonstrates a strong positive biodiversity-productivity relationship in a subtropical forest experiment, showing increased productivity with species richness and complementary effects over time.

This study uses a molecular tethering approach to enrich HP1alpha at telomeres, revealing its role in altering telomere structure and stability in cancer cells.

This paper introduces a method to generate DNA methylation variation in Arabidopsis thaliana by expressing a human TET enzyme, leading to hypomethylation and phenotypic changes.

The paper sequenced nine Verticillium species genomes to study their evolution, finding frequent chromosomal rearrangements and gene loss, with few species-specific genes.

This study uses super-resolution microscopy to show that mutations in RPGRIP1L and TCTN2 disrupt transition zone architecture in Joubert syndrome, affecting ciliary protein localization and signaling.

The paper identifies and characterizes two genes, CsMYB6A and CsUGT72AM1, that promote flavonoid accumulation in purple-leaf tea, with CsMYB6A activating structural genes and CsUGT72AM1 catalyzing flavonol glycosylation.

This study identifies AST1, a Trihelix transcription factor in Arabidopsis, which enhances abiotic stress tolerance by binding to AGAG-box and GT motifs, regulating stress-related genes and physiological traits.

The paper introduces a method combining CRISPR imaging and sequential DNA FISH to multiplex live genomic locus tracking, enabling identification of 7 elements with rapid FISH rounds and a registration algorithm.