X. Wang

This study creates GH5 cellulase hybrids from mesophilic and thermophilic parents to identify elements enhancing thermostability, finding improved thermal properties in some hybrids.

The paper combines proteomics and machine learning to generate a high-confidence apicoplast proteome in malaria parasites, identifying 346 proteins and validating novel functions.

This study finds that TP53 mutations in breast cancer increase immunogenic activity, suggesting they could be a biomarker for immunotherapy response.

This study evaluates how different pretreatments affect flavonoid content and antioxidant activity in Dryopteris erythrosora leaves, finding that shade drying followed by oven drying best preserves these properties.

This study identifies EZH2 automethylation as a regulatory mechanism that modulates PRC2 histone methyltransferase activity.

This study shows that SUMO paralogs determine the fate of WT and mutant CFTRs, with PIAS4 promoting biogenesis and reducing degradation.

This paper develops a live attenuated S. suis vaccine by deleting multiple virulence genes, showing it suppresses STSLS and provides ST-independent protection in mice.

The paper investigates speciation mechanisms in mangroves, finding that cycles of isolation and gene flow (MIM) drive speciation between oceanic regions, challenging the traditional model of strict allopatry.

This study investigates PU.1's pioneering activity in early T-cell development, showing its ability to bind and open closed chromatin sites despite lacking collaborators, and its role in regulating gene accessibility and transcription.

This study isolates and characterizes Bacillus amyloliquefaciens subsp. plantarum XH-9, showing it promotes plant growth and suppresses Fusarium oxysporum in wheat.

The paper demonstrates that chasing triplets in predation can allow more consumer species to coexist than resources, overcoming the competitive exclusion principle.

This study analyzes TCRB and IGH repertoires in IgAN patients to identify non-invasive biomarkers for diagnosis.

The paper shows that horizontal transfer of coumarate catabolism pathways into E. coli requires host mutations to function, as intermediates inhibit purine biosynthesis, and some mutations are already present in the native host.

The paper describes a new Early Cretaceous monocot fossil from the Yixian Formation, highlighting its morphological features and phylogenetic placement as an herbaceous monocot.

This study develops a DNA methylation-based classifier, BrainMETH, to categorize brain metastases by tissue origin and therapeutic subtypes using epigenetic profiling.

This paper develops a novel MDS patient-derived xenotransplantation model in MISTRG mice that faithfully represents all MDS subtypes and enables effective drug testing.

This study identifies mechanisms of extracellular vesicle (EV) biogenesis in Staphylococcus aureus and demonstrates their potential as a vaccine platform through engineered EVs.

This study identifies a non-scission role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells through interactions with SNX9.

This study identifies natural variation in OsLG3 that enhances drought stress tolerance in rice by improving ROS scavenging, offering a genetic resource for breeding drought-tolerant rice.

The paper identifies differentially expressed genes and SNPs associated with tame and aggressive behaviors in silver foxes.

The paper analyzes the global spread of the mcr-1 gene by sequencing isolates and phylogenetic analysis, finding all mcr-1 elements originated from a single mobilization event in the mid-2000s.

This study identifies immune-related gene-sets with higher expression in TNBC, associated with survival prognosis and immune features like Treg cells and immune checkpoints.

This study identifies reduced diffusional conductance to CO2 as the main factor limiting photosynthesis in salt-stressed rice leaves.

This study shows CRISPR-Cas9 can confer resistance to cauliflower mosaic virus by targeting coat protein sequences, leading to non-functional viral proteins and reduced infection.

The paper analyzes genetic diversity and adaptation in indigenous Chinese cattle, identifying genes associated with environmental adaptation and confirming historical admixture patterns.

This study determines the structure of human pro-myostatin and identifies features responsible for its latent state, offering insights into myostatin activation and potential inhibitor design.

This study uses DNA barcoding to analyze evolutionary patterns in British Euphrasia, finding that polyploidy drives genetic divergence but standard barcoding loci lack species-level resolution.

This study characterizes t-Darpp's structure, metal-binding, and phosphorylation by CDK1 and CDK5, revealing its monomeric form and calcium-binding properties.

The paper introduces a new method to estimate soil organic carbon stocks by accounting for soil volume changes, revealing an additional carbon sink in global forests.