Author

Y. Kou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Bioengineering· 1 Biophysics· 1 Cancer Biology· 1 Evolutionary Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 6 Organism:mouse· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:metabolomics· 2 Assay:metagenomics· 2

Frequent Co-Authors

X. Li· 4 shared L. Wang· 3 shared Y. Wang· 3 shared J. Qiu· 2 shared X. Wang· 2 shared Y. Tan· 2 shared Y. Zhou· 2 shared Z. Liu· 2 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersMicrobiology

X. Li

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Camel milk affects serum metabolites by modulating the intestinal microflora

H. Yue, J. Zhang, R. Wang, L. Zhao, Y. Kou, R. Li, Z. Yang, Y. Qian, X. Li, X. Wang, P. Yasheng, J. Wu, X. Xing, L. Xie, H. Niu, , F. Gao

This study shows that camel milk modulates gut microbiota and serum metabolites in rats, with beneficial bacteria and metabolites resembling those of healthy individuals.

bioRxiv · Dec 18, 2023 · PreprintMicrobiology

A murine commensal protozoan relieves Clostridium difficile infection through regulating the arginine metabolism and the host intestinal immune response

H. Yang, X. Wu, W. Zang, Y. Zhou, X. Li, L. Wang, W. Cui, Y. Kou, Y. Wang, B. Gu

This study identifies a murine gut protozoan that alleviates Clostridium difficile infection by modulating arginine metabolism and host immune responses.

bioRxiv · May 6, 2023 · PreprintMicrobiology

Multi-omics of the gut microbial ecosystem in the immunotherapy resistance in microsatellite instability-high gastrointestinal cancer patients

S. Cheng, Z. Han, X. Yin, D. Dai, F. Li, X. Zhang, M. Lu, Z. Lu, X. Wang, J. Zhou, J. Li, X. Guo, P. Song, C. Qiu, W. Shen, , Z. Peng

The paper uses multi-omics data to identify gut microbiome and metabolite markers of immunotherapy resistance in MSI-H/dMMR gastrointestinal cancer patients and develops a predictive model with 0.83 accuracy.

bioRxiv · Mar 7, 2023 · PreprintCancer Biology

OPAM, an Open source, 3D printed Low-cost Micro-Manipulator for Single Cell Manipulation

J. Xu, Z. Du, P. H. Liu, Y. Kou, L. Chen

The paper introduces OPAM, a low-cost, 3D-printed micromanipulator for single cell manipulation, demonstrating its ability to capture and transfer single cells under a microscope.

bioRxiv · Aug 9, 2021 · PreprintBioengineering

Structural insights into the activation of human calcium-sensing receptor

X. Chen, L. Wang, Z. Ding, Q. Cui, L. Han, Y. Kou, W. Zhang, H. Wang, X. Jia, M. Dai, Z. Shi, Y. Li, X. Li, Y. Geng

The paper presents cryo-EM structures of the human calcium-sensing receptor in inactive and active states, revealing structural changes during activation.

bioRxiv · Mar 30, 2021Biophysics

Polycomb repressive complex 2 coordinates with Sin3 histone deacetylase complex to epigenetically reprogram genome-wide expression of effectors and regulate pathogenicity in Magnaporthe oryzae

Z. Wu, J. Qiu, H. Shi, C. Lin, J. Yue, Z. Liu, W. Xie, Y. Kou, z. Tao

The paper shows that Polycomb repressive complex 2 and Sin3 histone deacetylase complex work together to epigenetically control effector gene expression in Magnaporthe oryzae, regulating its pathogenicity.

bioRxiv · Mar 21, 2021 · PreprintMicrobiology

Establishment and Resilience of Transplanted Gut Microbiota in Aged Mice

Y. Wang, J. Tang, Q. Lv, Y. Tan, X. Dong, H. Liu, N. Zhao, Z. He, Y. Kou, Y. Tan, X.-a. Liu, L. Wang, Y.-Y. Liu, L. Dai

This study investigates how age-matching between fecal microbiota transplantation (FMT) donors and aged recipients affects microbiota establishment and resilience, finding that mismatched age may reduce resilience against inflammation.

bioRxiv · Mar 18, 2021Microbiology

Evolutionary genomics of structural variation in Asian rice (Oryza sativa) and its wild progenitor (O. rufipogon)

Y. Kou, Y. Liao, T. Toivainen, Y. Lv, X. Tian, J. J. Emerson, B. S. Gaut, Y. Zhou

This study identifies structural variants in Asian rice and its wild ancestor, finding they are predominantly deleterious and contribute to domestication costs and agronomic trait changes.

bioRxiv · Dec 19, 2019Evolutionary Biology

Mitochondrial dynamics and mitophagy are necessary for proper invasive growth in Rice Blast

Y. Kou, Y. He, J. Qiu, Y. Shu, F. Yang, Y. Deng, N. I. Naqvi

This study shows that mitochondrial dynamics and mitophagy are essential for the invasive growth of Magnaporthe oryzae during rice blast disease.

bioRxiv · Mar 30, 2019Pathology

The gut microbiota regulates mouse biliary regenerative responses

W. Liu, C. Yan, B. Zhang, R. Chen, Q. Yu, X. Li, Y. Zhang, H. Hua, Y. Wei, Y. Kou, Z. Liu, R. Tang, K. Zheng, Y. Wang

This study shows that gut microbiota influences biliary regenerative responses in mice, with butyrate playing a role in inhibiting fibrosis.

bioRxiv · Mar 12, 2019 · PreprintMicrobiology