Author
Y. Liu
Chinese Academy of Sciences
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Same name, identified by ORCID
Biology Disciplines
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2022-2023 · peak 23/yrCo-Author Collaboration Network
10 top collaborators · 14 mutual co-author links815 papers
Recent·Most cited
- Cancer BiologybioRxiv
Oncogene-like addiction to aneuploidy in human cancers
V. Girish, A. A. Lakhani, C. M. Scaduto…·J. M. Sheltzer
This study demonstrates that trisomy of chromosome 1q is essential for malignant growth in cancers and shows that TP53 mutations are mutually exclusive with 1q aneuploidy.
DOI 10.1126/science.adg4521 - BiochemistrybioRxivPreprint
A pilot study of stable isotope fractionation in Bombyx mori rearing
This study measures stable isotope fractionation in Bombyx mori strains across life stages to trace isotope movement and understand fractionation patterns.
DOI 10.1101/2023.01.08.523185 - Plant BiologybioRxiv
Innate immunity can distinguish beneficial from pathogenic rhizosphere microbiota
D. Thoms, M. Y. Chen, Y. Liu…·C. H. Haney
The paper shows that plants can distinguish between beneficial and pathogenic Pseudomonas fluorescens strains through distinct immune responses.
DOI 10.1016/j.celrep.2025.116457 - ImmunologyBiomaterialsPeer-reviewed
Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge
S. Sun, E. Li, G. Zhao…·S. Guan
This study shows that peptide-poloxamine-DNA nanoparticles provide complete protection against lethal SARS-CoV-2 challenge through robust mucosal immunity.
DOI 10.1016/j.biomaterials.2022.121907 - BioengineeringbioRxivPreprint
Deep learning-based predictive identification of functional subpopulations of hematopoietic stem cells and multipotent progenitors
S. Wang, J. Han, J. Huang…·J. Huang
This study develops a deep learning model to classify hematopoietic stem cells and multipotent progenitors using light microscopy images, demonstrating its effectiveness in distinguishing functional subpopulations.
- Cancer BiologybioRxivPreprint
Comparative transcriptome revealed potential genes related with drug resistance in Melanoma
B. Zhao, Y. Liu, X. Tang, S. Cheng
The paper identifies SENP1 and Hippo signaling pathway activation as factors contributing to drug resistance in melanoma using transcriptomic and functional analyses.
DOI 10.1101/2022.12.14.520500 - EcologybioRxivPreprint
Drivers of the negative diversity-invasibility relationship: nutrient availablity, allelopathy, soil biota and soil legacy effects
A. Oduor, M. van Kleunen, Y. Liu
The study tests mechanisms driving the negative diversity-invasibility relationship using experiments on nutrient availability, allelopathy, soil biota, and soil legacy effects in native and invasive plant species.
DOI 10.1101/2022.12.11.519939 - Cell BiologybioRxiv
Disruption of the nuclear localization signal in RBM20 is causative in dilated cardiomyopathy
Y. Zhang, Z. R. Gregorich, Y. Wang…·W. Guo
This study identifies disruption of the nuclear localization signal in RBM20 as a causative mechanism in dilated cardiomyopathy through impaired nucleocytoplasmic transport.
- EcologybioRxivPreprint
The more synthetic polymer types pollute the soil, the stronger the growth suppression of invasive alien and native plants
Y. Fu, M. van Kleunen, K. Ma, Y. Liu
This study shows that increased diversity of synthetic polymer types in soil leads to stronger growth suppression of both invasive and native plants, with more pronounced effects on invasive species.
DOI 10.1101/2022.12.08.519663 - BiophysicsbioRxivPreprint
In situ quantification of osmotic pressure within living embryonic tissues
A. Vian, M. Pochitaloff, S.-T. Yen…·O. Campas
The paper introduces a method to measure osmotic pressure in living tissues and finds a balance between intracellular and interstitial pressures in zebrafish embryos.
- Cell BiologybioRxivPreprint
Identifying transcriptomic downstream targets of genes commonly mutated in Hereditary Hemorrhagic Telangiectasia
M. K. Ali, Y. Liu, K. Schimmel…·E. Spiekerkoetter
This study identifies common downstream transcriptomic targets of HHT-causing genes and discovers Brivanib as a potential therapeutic for HHT.
DOI 10.1101/2022.11.25.517570 - BioengineeringbioRxivPreprint
Effects of cardiac function alterations on the risk of postoperative thrombotic complications in patients receiving endovascular aortic repair
This study uses a computational model to show that ventricular systolic function affects thrombus formation after EVAR, with specific correlations identified.
- BiochemistrybioRxivPreprint
O-GlcNAcylation promotes YTHDF1 cytosolic localization and colorectal cancer tumorigenesis
J. Li, M. Ahmad, L. Sang…·J. Li
This study shows O-GlcNAcylation of YTHDF1 enhances its cytosolic localization and promotes colorectal cancer by increasing c-Myc expression.
DOI 10.1101/2022.11.21.517456 - BiochemistrybioRxivPreprint
Urine proteomic analysis of the rat e-cigarette model
Y. Liu, Z. Shen, C. Zhao, Y. Gao
This study uses urine proteomics to analyze the effects of e-cigarettes on rats, identifying differential proteins and pathways linked to immune, cardiovascular, and respiratory systems.
DOI 10.1101/2022.11.19.517186 - BiochemistrybioRxivPreprint
Urine proteomic analysis of the rat startle model
The paper uses urine proteomics to detect startle-induced changes in rats, identifying differential proteins related to neurotransmitter and glucose transport.
DOI 10.1101/2022.11.19.517176 - BiophysicsbioRxiv
CryoEM Reveals Oligomeric Isomers of a Multienzyme Complex and Assembly Mechanics
J. K. J. Lee, Y. Liu, J. J. Hu…·Z. H. Zhou
This study uses cryoEM to reveal the oligomeric isomers and assembly mechanics of PCC from Leishmania tarentolae, showing how subunit attachment affects enzymatic activity.
DOI 10.1016/j.yjsbx.2023.100088 - ImmunologybioRxivPreprint
The Cul5 E3 Ligase Complex Is a Key Negative Feedback Regulator of TCR/IL2 Signaling and Anti-Tumor Activity in CD8+ T Cells
This study identifies Cul5 as a negative feedback regulator of CD8+ T cell signaling and anti-tumor activity, showing its knockout enhances tumor control through proteomic and signaling changes.
- Cell BiologybioRxivPreprint
A stable reference human transcriptome and proteome as a standard for reproducible omics experiments
S. Lu, H. Lu, T. Zheng…·G. Zhang
The paper establishes a stable human cell line as a reference for transcriptomic and proteomic studies, showing consistent results across generations and platforms.
DOI 10.1101/2022.11.16.516732 - MicrobiologybioRxivPreprint
Legionella pneumophila modulates host cytoskeleton by an effector of transglutaminase activity
This study identifies RavJ as an effector of Legionella pneumophila that crosslinks actin with Motin proteins, inhibiting actin depolymerization and modulating host cytoskeleton.
DOI 10.1101/2022.11.15.516567 - BiochemistrybioRxivPreprint
Formation process of the twinning β-form anhydrous guanine platelets in the scallop eyes
This study reports the formation mechanism of twinning β-form anhydrous guanine microplatelets in scallop eyes, revealing an intermediate amorphous phase and a two-step crystallization process.
DOI 10.1101/2022.11.14.516375 - PathologybioRxivPreprint
Novel inhibitors against COVID-19 main protease suppressed viral infection
V. Ramachandran, Y. Liu, Q. He…·R. Chang
This study identifies novel small-molecule inhibitors of SARS-CoV-2 main protease that suppress viral replication in human cells.
DOI 10.1101/2022.11.05.515305 - Cell BiologybioRxivPreprint
Integrated transcriptome and lineage analyses reveal novel catecholaminergic cardiomyocytes contributing to the cardiac conduction system in murine heart
T. Sun, A. Grassam-Rowe, Z. Pu…·M. Lei
This study identifies a novel catecholaminergic cardiomyocyte population expressing Dbh that contributes to the murine cardiac conduction system through transcriptomic, genetic, and optogenetic analyses.
- BioengineeringbioRxivPreprint
Characterization of N distribution in different organs of winter wheat using UAV-based remote sensing
This study evaluates UAV-based remote sensing for predicting nitrogen content and nitrogen agronomic efficiency in winter wheat organs using vegetation indices and texture features.
DOI 10.1101/2022.11.02.514839 - Cancer BiologybioRxivPreprint
Alveolar epithelial type 1 cells serve as a cell of origin for lung adenocarcinoma with distinct molecular and phenotypic presentation
M. Yang, H. Shen, P. Flodby…·C. N. Marconett
This study identifies alveolar epithelial type 1 cells as a potential cell of origin for lung adenocarcinoma, showing distinct molecular and histological features based on cell of origin.
DOI 10.1101/2022.10.29.514334 - BioengineeringbioRxiv
Improving the sensitivity of in vivo CRISPR off-target detection with DISCOVER-Seq+
R. S. Zou, Y. Liu, O. E. Reyes Gaido…·T. Ha
DISCOVER-Seq+ improves CRISPR off-target detection sensitivity by using DNA-PKcs inhibition and ChIP-seq to identify more off-target sites in cells and mice.