Author
Y. Zhang
Beijing University of Technology
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Same name, identified by ORCID
Biology Disciplines
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2019-2020 · peak 23/yrCo-Author Collaboration Network
10 top collaborators · 14 mutual co-author links947 papers
Recent·Most cited
- MicrobiologybioRxivPreprintDOI 10.1101/2020.01.20.912535
- MicrobiologybioRxivPreprint
Remodeling gut microbiota by Streptococcus thermophilus 19 attenuates inflammation in septic mice
F. Han, Y. Zhang, X. Yang…·D. Hu
This study shows that S. thermophilus 19 reduces inflammation in septic mice by remodeling gut microbiota.
DOI 10.1101/543967 - Cancer BiologybioRxiv
Fusobacterium nucleatum host cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration
M. A. Casasanta, C. C. Yoo, B. Udayasuryan…·D. J. Slade
This study shows that Fusobacterium nucleatum binding and invasion of colorectal cancer cells induces IL-8 and CXCL1 secretion, promoting cancer cell migration and immune signaling.
DOI 10.1126/scisignal.aba9157 - Animal Behavior & CognitionbioRxivPreprint
Diversified Learning Environment Alleviates Learning Impairment Caused by Contextual Stress
C. Gong, M. Zhang, Y. Zhang…·X. Liu
This study shows that a diversified learning environment improves active avoidance learning and mitigates stress-induced learning impairments in animals.
DOI 10.1101/2020.01.15.907840 - Cell BiologybioRxiv
mTORC2 mediate FLCN-induced HIF2α nuclear import and proliferation of clear cell renal cell carcinoma
DOI 10.3389/fmolb.2020.00121 - MicrobiologybioRxivPreprint
Role of DNA Methylation in Persister Formation in Uropathogenic E. coli
Y. Xu, S. Liu, W. Zhang, Y. Zhang
This study investigates the role of DNA methylation in persister formation in UPEC, showing that the dam mutant has a defect in persister formation and identifies associated transcriptional and metabolic changes.
DOI 10.1101/2020.01.07.897686 - MicrobiologyJournal of Veterinary SciencePeer-reviewed
Complete genome and phylogenetic analysis of bovine papillomavirus type 15 in Southern Xinjiang dairy cow
j. hu, W. Zhang, S. S. Chauhan…·Wanqi Zhang, Surinder Singh Chauhan, Changqing Shi, Yumeng Song, Zhitao Qiu, Yubing Zhao, Jianjun Hu
The paper reports the complete genome sequence of a novel BPV type 15 strain from a cow in southern Xinjiang and places it phylogenetically within the Xipapillomavirus genus.
DOI 10.4142/jvs.2020.21.e73 - ImmunologybioRxivPreprint
Acetylation is required for NLRP3 self-aggregation and full activation of the inflammasome
K. Zhao, Y. Zhang, X. Xu…·B. Lu
This study identifies acetylation as essential for NLRP3 inflammasome activation, showing that KAT5-mediated acetylation promotes NLRP3 aggregation and inflammasome assembly.
DOI 10.1101/2019.12.31.891556 - BiochemistrybioRxiv
XACT-seq comprehensively defines the promoter-position and promoter-sequence determinants for initial-transcription pausing
J. T. Winkelman, C. Pukhrambam, I. O. Vvedenskaya…·B. E. Nickels
XACT-seq identifies promoter-position and sequence determinants for initial-transcription pausing in Escherichia coli by measuring RNAP-active-center position relative to DNA with single-nucleotide resolution.
- BioengineeringbioRxiv
Dihydroartemisinin-loaded Magnetic Nanoparticles for Enhanced Chemodynamic Therapy
S. Guo, X. Yao, Q. Jiang…·W. Yang
This study develops dihydroartemisinin-loaded magnetic nanoparticles to enhance chemodynamic therapy, showing improved ROS production and efficacy against breast cancer cells, including drug-resistant ones.
DOI 10.3389/fphar.2020.00226 - Cell BiologybioRxiv
Glucose starvation to rapid death of Nrf1, but not Nrf2, deficient hepatoma cells from its fatal defects in the redox metabolism reprogramming
Y.-p. Zhu, Z. Zheng, X. Xiang, Y. Zhang
This study shows Nrf1-deficient hepatoma cells die rapidly under glucose starvation due to redox metabolism defects, unlike Nrf2-deficient cells.
DOI 10.1155/2020/4959821 - MicrobiologybioRxivPreprint
Fibroblast Protection of Borrelia burgdorferi from Doxycycline, Cefuroxime and Daptomycin Combination is Eliminated by Oregano or Carvacrol Essential Oil
C. Bai, H. Yang, P. Cui…·Y. Zhang
The paper shows fibroblasts protect B. burgdorferi from a drug combination, but oregano or carvacrol essential oil enhances drug efficacy against the bacteria in fibroblasts.
DOI 10.1101/861575 - ZoologybioRxiv
Effects of host plants nutrient on the nutrient in Bradysia cellarum and Bradysia impatiens
Y. Gou, P. Quandahor, Y. Zhang, C. Liu
This study examines how different host plant nutrients affect the nutrient content of Bradysia cellarum and Bradysia impatiens after three generations of feeding.
DOI 10.1371/journal.pone.0226471 - MicrobiologybioRxivPreprint
A Novel LysR-Type Global Regulator RpvA Controls Persister Formation and Virulence in Staphylococcus aureus
J. Han, Z. Liu, T. Xu…·Y. Zhang
This study identifies RpvA, a LysR-type regulator in S. aureus, which controls persister formation and virulence by modulating metabolism and virulence gene expression.
DOI 10.1101/861500 - MicrobiologyMicrobiologyPeer-reviewed
Variation in genome content and predatory phenotypes between Bdellovibrio sp. NC01 isolated from soil and B. bacteriovorus type strain HD100
L. E. Williams, N. Cullen, J. A. DeGiorgis…·Y. Zhang
This study compares genome content and predatory phenotypes between Bdellovibrio sp. NC01 and B. bacteriovorus HD100, revealing differences in prey range and predation efficiency linked to horizontal gene transfer.
DOI 10.1099/mic.0.000861 - BiochemistrybioRxiv
RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription
L. Li, V. Molodtsov, W. Lin…·Y. Zhang
This paper reports crystal structures showing the stepwise displacement of the σ finger in bacterial transcription initiation factors driven by RNA extension during initial transcription.
DOI 10.1073/pnas.1920747117 - BiophysicsbioRxivPreprint
Modulating the cellular context broadly reshapes the mutational landscape of a model enzyme
S. Thompson, Y. Zhang, C. Ingle…·T. Kortemme
The paper shows that the absence of the protease Lon in E. coli reshapes the mutational landscape of DHFR, increasing the proportion of advantageous mutations.
DOI 10.1101/848010 - Cell BiologybioRxiv
TurboID-mediated proximity labelling of cytoophidium proteome in Drosophila
The paper applies TurboID-mediated biotinylation to characterize the cytoophidium proteome in Drosophila, demonstrating its utility for studying subcellular compartments.
DOI 10.1093/g3journal/jkab077 - ImmunologyFrontiers in ImmunologyPeer-reviewed
Host-Microbial Interactions in Systemic Lupus Erythematosus and Periodontitis
L. Pessoa, G. Aleti, S. Choudhury…·M. Freire
This study investigates the relationship between periodontal microbiota and systemic inflammation in SLE patients, finding that periodontal pathogens correlate with increased proinflammatory cytokines.
DOI 10.3389/fimmu.2019.02602 - Plant BiologybioRxivPreprint
RNA G-quadruplex structures exist and function in vivo
X. Yang, J. Cheema, Y. Zhang…·Y. DING
The paper identifies RNA G-quadruplex structures in Arabidopsis and rice, showing they regulate translation and plant growth.
DOI 10.1101/839621 - Plant BiologybioRxiv
In vivo nuclear RNA structurome reveals RNA-structure regulation of mRNA processing in plants
Y. DING, Z. Liu, Q. Liu…·J. Cheema
The paper uses SHAPE profiling to study RNA structure in Arabidopsis nuclei and identifies structural features linked to mRNA splicing and polyadenylation.
DOI 10.1186/s13059-020-02236-4 - Evolutionary BiologybioRxivPreprint
The Out of East Asia model versus the African Eve model of modern human origins in light of ancient mtDNA findings
The paper compares the Out of East Asia and African Eve models of modern human origins using ancient mtDNA data, finding that basal R is older than basal N, supporting the East Asia model.
DOI 10.1101/546234 - Evolutionary BiologybioRxivPreprint
Variation in the life history strategy of cells underlies tumor’s functional diversity
This study applies r- and K-selection to HeLa cells to show how life history strategies influence tumor functional diversity through gene expression and ecological competition.
DOI 10.1101/829135 - EcologybioRxivPreprint
Synergism of gut microbiota to double-stranded RNAs in RNA interference of a leaf beetle
L. Xu, S. Xu, L. Sun…·J. Zhang
This study shows gut bacteria enhance dsRNA-induced mortality in leaf beetles by accelerating dsRNA degradation and causing microbiota dysbiosis.
DOI 10.1101/824581 - MicrobiologybioRxivPreprint
A novel antiviral lncRNA EDAL shields a T309 O-GlcNAcylation site to promote EZH2 degradation
L. Zhao, B. Sui, D. Chen…·Y. Zhang
This paper identifies a long non-coding RNA, EDAL, that inhibits neurotropic viruses by promoting EZH2 degradation through O-GlcNAcylation site interference.
DOI 10.1101/824813 - MicrobiologybioRxiv
Prevalence of beta-lactam drug-resistance genes in commensal Escherichia coli contaminating ready-to-eat lettuce
N. Liao, J. Rubin, Y. Hu…·L. W. Riley
This study found that a significant proportion of E. coli isolates from ready-to-eat lettuce in Northern California carry beta-lactam resistance genes, posing a potential risk for human infections.
DOI 10.1089/fpd.2020.2792 - BioengineeringbioRxiv
A novel MRI-based finite element modeling method for calculation of myocardial ischemia effect in patients with functional mitral regurgitation.
Y. Zhang, V. Y. Wang, A. E. Morgan…·M. B. Ratcliffe
This paper introduces an MRI-based finite element modeling method to predict myocardial ischemia effects in patients with functional mitral regurgitation, showing successful convergence and agreement with experimental data.
- BiophysicsbioRxiv
A complex structure of arrestin-2 bound to a G protein-coupled receptor
W. Yin, Z. Li, M. Jin…·H. E. Xu
The paper reports the structure of arrestin-2 bound to neurotensin receptor 1, revealing a novel orientation that enables coupling to GPCRs lacking a C-terminal tail.
DOI 10.1038/s41422-019-0256-2 - Cancer BiologyBMC CancerPeer-reviewed
Migration of gastric cancer is suppressed by rabies virus glycoprotein via regulating α7-nicotinic acetylcholine receptors/ERK-EMT
X. Bu, A. Zhang, Z. Chen…·Y. Yan
This study shows that rabies virus glycoprotein suppresses gastric cancer migration by inhibiting the 7-nAChR-MEK/ERK-EMT pathway.
DOI 10.1186/s12885-019-6225-9 - ImmunologybioRxivPreprint
Large-scale Analysis of 2,152 dataset reveals key features of B cell biology and the antibody repertoire
Z. Zhang, X. Yang, M. Wang…·X. Yu
This study analyzes 2,152 antibody repertoires to identify key features of B cell biology, revealing gene usage patterns, sex preferences, and mutability mechanisms in the antibody repertoire.