Y. Zhang

The paper determines the spatial arrangement of Sin3 subunits around SIN3A using cross-linking and mass spectrometry, revealing their relative positions and interactions.

This study identifies NMNAT as a chaperone that prevents phosphorylated Tau aggregation in vitro and reduces pathology in a fly model.

This study shows that cargo-free scaffolds recruit metastatic cancer cells through a lung-mimicking myeloid cell S100A8/A9 axis, reducing lung metastasis.

The paper studies how molecular reach and diffusivity affect reaction efficacy in membrane-confined systems, showing that increasing reach can enhance or reduce efficacy depending on diffusion rates.

The paper assesses the frequency of deleterious mutations in 21 hereditary breast and ovarian cancer genes among 882 high-risk Chinese individuals, finding 19.5% carried such mutations, with higher rates in those with both breast and ovarian cancer histories.

This paper presents a 3D printed microheater integrated microneedle patch system for controlled drug delivery, demonstrating its integration with wearable electronics for pain management.

This study shows that the 5’-NAD cap of RNAIII in Staphylococcus aureus modulates toxin production and virulence by affecting toxin expression without altering RNA structure.

The paper introduces a dual nanopore technique called 'flossing' to improve DNA mapping by reducing molecular noise through repeated scans and increasing linearization efficiency.

This study compares the gut microbiome of short-term and long-term medical workers to normal controls, finding significant structural changes linked to hospital exposure.

This study compares the shapes and sizes of prostate lesions in dogs treated with laser, radiofrequency, and microwave ablation, finding significant differences in lesion morphology and volume.

The paper identifies a unique adipocyte population in bone marrow, MERAs, that regulate bone and vessel homeostasis through single-cell transcriptomics in mice.

This paper establishes a novel human HCC patient-derived xenograft model in immunocompetent mice, showing high tumor formation rates and preserved tumor characteristics.

This paper shows that the bacterial T6SS effector EvpP inhibits neutrophil recruitment by suppressing Jnk-Caspy inflammasome signaling in zebrafish larvae during infection.

This study identifies a novel J-binding protein complex involved in RNA Polymerase II transcription termination in trypanosomes, linking base J modification to termination regulation.

This study shows that synonymous SNPs in viral genes of WSSV reduce RNAi effectiveness by causing siRNA-target mismatches, allowing the virus to evade host immunity.

The paper uses QTL mapping to show MHC variants bias TRBV gene usage in UCB samples, revealing germline-encoded TCR-MHC contacts influence TCR repertoire.

This paper develops a winner(s)-take-all method for nonlinear amplification of DNA-encoded libraries, demonstrating its application in decoding DNA-encoded chemical libraries.

This study shows that loss of the ATRX/DAXX complex disrupts rDNA heterochromatinization, leading to increased rDNA transcription and promoting glioma development.

This study shows that 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic mice by scavenging reactive dicarbonyls and improving HDL function.

This study examines how shift-work affects carotid artery health and cerebral blood flow in SHR and WKY rats, finding increased blood pressure, arterial thickening, and reduced blood flow.

The paper reports the cryo-EM structure of the human MLL1 complex bound to the nucleosome, revealing how it interacts with histone H3K4 and promotes tri-methylation.

This study shows that absence of geomagnetic field reduces feeding in brown planthopper nymphs, leading to lower body weight and altered glucose levels and appetite-related gene expression.

The paper examines the roles of three wheat glutamine synthetase isozymes in nitrogen assimilation and translocation, showing distinct functions and synergistic effects.

The paper estimates protein sequence evolution rates in the Paniceae tribe to infer the evolutionary pathway of C4 photosynthesis, suggesting a C2 intermediate.

The paper examines sex differences in the blood lipidome across three cohorts, finding that 60% of lipids differ between men and women, with distinct lipid class distributions.

The paper links carotenoid oxidation and feather redness to mitochondrial function in house finches, showing a direct relationship between mitochondrial performance and feather coloration.

This study identifies essential oils with antimicrobial activity against stationary phase Staphylococcus aureus persisters and evaluates their combination with antibiotics.

This study shows that engineering CAR-T cells with CD103 improves their anti-tumor efficacy against E-cadherin positive tumors by enhancing infiltration, expansion, and persistence in vivo.

This study shows mDia2 interacts with catenins to regulate adherens junctions in ovarian cancer cells, affecting actin polymerization and cell-cell adhesion.

This study determines the structure of an E. coli transcription activation complex and shows that Crl stabilizes σS to activate transcription without DNA contact.