Natalia V. Gounko

Presynaptic Release Probability Determines the Need for Sleep

The paper shows that presynaptic release probability, not synaptic strength, decreases with sleep loss and affects sleep need across species.

EndophilinA-dependent coupling between activity-dependent calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation

The paper shows how EndophilinA couples calcium influx to synaptic autophagy and identifies a Parkinson-risk mutation that disrupts this process.

Species-specific mitochondria dynamics and metabolism regulate the timing of neuronal development

This study shows that slower mitochondrial development and lower metabolic activity in human cortical neurons compared to mice delay neuronal maturation, and stimulating mitochondria accelerates this process.

Corticotropin-Releasing Factor Induces Functional And Structural Synaptic Remodelling In Acute Stress

This study shows CRF rapidly alters synaptic function and structure in hippocampal CA1 neurons during acute stress, enhancing synaptic communication and memory consolidation.

Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer

The paper identifies IgSF8 as a regulator of hippocampal CA3 microcircuit development by analyzing cell-surface protein composition and synaptic interactions.

Parl Deficiency In Mouse Causes Coenzyme Q Depletion, Complex III Defects, And Leigh-Like Syndrome

This study shows that Parl deficiency in mice leads to mitochondrial dysfunction, Complex III defects, and Leigh-like syndrome, highlighting its critical role in neurological health.