Julia E. Robbins

Structure-free, site-resolved contrastive learning extends small-molecule discovery beyond the reach of structure-based modeling

Ptarmigan-1 uses contrastive learning to predict small molecule-protein interactions without requiring 3D structure, outperforming traditional methods on challenging targets.

MSstatsBioNet: Integrating Statistical Analyses with Prior Knowledge Biomolecular Networks for Quantitative Proteomics and Phosphoproteomics

MSstatsBioNet integrates differential proteomics results with biomolecular networks to enable mechanistic interpretation of biological changes.

CpG island density predicts CBP/p300 dependency across 3D chromatin clusters

The paper identifies two classes of Pol2-mediated chromatin clusters and shows CpG island density predicts CBP/p300 dependency.

Native, Spatiotemporal Profiling of the Global Human Regulome

This paper introduces a method to profile the regulome across human cell lines and perturbations, revealing transcription factor dynamics and drug responses.

A framework for quality control in quantitative proteomics

The paper introduces a framework for quality control in quantitative proteomics, combining internal and external QC measures with tools for data analysis and deposition.

Hippocampus Glutathione S Reductase Potentially Confers Genetic Resilience to Cognitive Decline in the AD-BXD Mouse Population

The paper identifies a genetic locus and protein associated with resilience to cognitive decline in AD-BXD mice and links it to human AD traits.