Author

Éric Solary

InsermORCID 0000-0002-8629-1341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 3 Research Focus:differential expression· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2

Frequent Co-Authors

Dorothée Selimoglu‐BuetiD· 4 shared Nathalie M DroiniD· 3 shared Aline RennevilleiD· 2 shared Aygun Imanci· 2 shared Françoise PorteuiD· 2 shared Lucie LaplaneiD· 2 shared Margot Morabito· 2 shared Philippe RameauiD· 2 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

Dorothée Selimoglu‐BuetORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

AXL mediates mast cell survival and resistance to tyrosine kinase inhibitors in mastocytosis

Kitsada Kangboonruang, Philippe Drabent, Fatlinda Maksut, Maxime Heintzé, Yves Lepelletier, Ludovic Lhermitte, Mélanie Féroul, Sébastien Letard, Caroline Kabore, Fabienne A. Brenet, C. Méni, Nicolas Cagnard, Vincent Bondet, Guillaume Lefèvre, Julie Bruneau, , Leïla Maouche-Chrétien

This study identifies AXL as a driver of mast cell survival and TKI resistance in mastocytosis and shows that dual KIT/AXL inhibition restores TKI sensitivity.

bioRxiv · Nov 3, 2025 · PreprintCancer Biology

Pro-inflammatory role of granzyme K producing bystander CD8+ T cells in acute myeloid leukemia

Lisa Aziez, Nicolas Deredec, Ismaël Boussaid, Carolyn Shasha, Romain Vazquez, Chloé Friedrich, Ania Alik, Kanchanadevi Manasse, Zoé Fremont-Debaene, Alexandra Barthelemy, Cyril Catelain, Philippe Rameau, Marguerite Vignon, Justine Decroocq, Olivier Kosmider, , Yannick Simoni

This study identifies a pro-inflammatory role of Granzyme K-producing bystander CD8+ T cells in AML, which promote IL-8 secretion and may exacerbate disease progression.

bioRxiv · Aug 12, 2025 · PreprintImmunology

Granulocyte Derived Resistin Inhibits Monocyte Maturation and Induces Immune Suppression in CMML

Nathan J. Hull, Rachel Cant, Laura A Guest, Yu‐Hung Wang, Kristian Gurashi, Roberto Paredes, Hector Huerga Encabo, Chien‐Chin Lin, Hwei‐Fang Tien, Robert Sellers, Sudhakar Sahoo, Dominique A. Bonnet, Dorothée Selimoglu‐Buet, Éric Solary, Daniel H. Wiseman, Kiran Batta

This study identifies granulocyte-derived resistin as a key factor in CMML that inhibits monocyte maturation and promotes immune suppression.

bioRxiv · Mar 3, 2025 · PreprintCancer Biology

CXCL8 secreted by immature granulocytes inhibits wildtype hematopoiesis in chronic myelomonocytic leukemia

Paul Deschamps, Margaux Wacheux, Axel Gosseye, Margot Morabito, Arnaud Pagès, Anne-Marie Lyne, Alexia Alfaro, Philippe Rameau, Aygun Imanci, Rabie Chelbi, Valentine Marchand, Aline Renneville, Mrinal M. Patnaik, Valérie Lapierre, Bouchra Badaoui, , Dorothée Selimoglu‐Buet

The paper identifies CXCL8 secreted by immature granulocytes as a factor inhibiting wildtype hematopoiesis in CMML, suggesting CXCL8 blockade could slow disease progression.

Journal of Clinical Investigation · Sep 17, 2024Peer-reviewedCancer Biology

Translational control of cell plasticity drives 5-FU tolerance

Mounira Chalabi‐Dchar, Olivia Villeronce, Julie Ripoll, Anne Vincent, Tanguy Fenouil, Rita Khoueiry, Jérôme Kucharczak, Laura Jentschel, Frédéric Catez, Arnaud M. Vigneron, Julie Tréguier, Celine MANDIER, Céline Bouclier, Jihane Boubaker-Vitre, Louise LAGERQVIST, , Jean‐Jacques Diaz

The paper shows 5-FU induces translational reprogramming in colorectal cancer cells, enhancing drug tolerance through pro-tumoral gene expression and IL-8 overexpression.

bioRxiv · Jul 3, 2024 · PreprintCancer Biology

Targeting Heterochromatin Eliminates Malignant Stem Cells in Chronic Myelomonocytic Leukemia Through Reactivation of Retroelements and Innate Immune pathways

Donia Hidaoui, Audrey Porquet, Rabie Chelbi, Mathieu Bohm, Aikaterini Polyzou, Vincent Alcazer, Stéphane Depil, Aygun Imanci, Margot Morabito, Aline Renneville, Dorothée Selimoglu-Buet, Sylvain Thépot, Raphael Itzykson, Lucie Laplane, Nathalie Droin, , Françoise Porteu

This study shows that combining DNA hypomethylating agents with H3K9me2 inhibitors reactivates immune pathways and eliminates malignant stem cells in CMML by targeting heterochromatin disorganization.

bioRxiv · Feb 2, 2024Cancer Biology