Hilda Amalia Pasolli

This study develops a method to derive and maintain specific subtypes of human midbrain dopaminergic neurons in vitro, revealing their functional and molecular characteristics and potential vulnerability in disease.

This study shows that VPS4 and CHMP7 are required for releasing centromeres from the nuclear envelope after mitosis, preventing DNA damage and ensuring proper positioning.

This study shows that luminal prostatic epithelial cells depend on AR signaling for survival and differentiation, and their loss triggers compensatory pathways and lineage plasticity.

The paper identifies a female-controlled lock-and-key mating mechanism in Aedes mosquitoes, showing how genital structures determine mating success and species competition.

This study uses single-particle tracking and 3D FIB-SEM to reveal dynamics and organization of individual vimentin filaments within dense networks, showing bidirectional motion and minimal local co-alignment with microtubules.

This study shows that Astn2 knockout mice display ASD-like behaviors and altered cerebellar circuit properties, including changes in synaptic transmission and glial volume.

This study demonstrates that Ebola virus VP24 undergoes nuclear trafficking via IMPA and its nuclear export signal (NES) is critical for nucleocapsid formation and infectivity.

The paper shows that reorganizing the hair follicle niche architecture can still support organ function, though it may lead to premature differentiation and reduced hair production.

The paper shows zebrafish stripe patterns arise from in situ differentiation of iridophore crystallotypes, not migration, with distinct transcriptomic and physiological states in stripe and interstripe regions.

The paper shows that astrocytes detoxify fatty acids from hyperactive neurons through mitochondrial oxidation, protecting neurons from toxicity.

The paper combines expansion and lattice light sheet microscopy to enable high-speed, nanoscale molecular imaging of neural circuits across large volumes.