Gut microbiota and health

The paper introduces a Bayesian Dirichlet process model to analyze microbiome associations with host phenotypes, showing high statistical power in simulated and real datasets.

This study shows that gum Arabic improves gut microbiota and brain metabolism in zebrafish but reduces reproductive fitness in females.

This study identifies gender-specific microbial dysbiosis in pancreatic cancer patients using microbiome data from 191 samples, revealing sex-related differences in bacterial composition and abundance.

This study investigates how bacterial supplements reduce radiation-induced brain metabolic changes in rats via the gut-brain axis using multi-omics approaches.

This study meta-analyzes 16S rRNA sequencing studies on gut microbiota and type 2 diabetes, finding significant heterogeneity but no consistent differences between diabetic and non-diabetic groups.

This study examines how carbamate and pyrethroid pesticides affect bile acid profiles in an in vitro gut microbiota model, showing changes in bile acid ratios and microbial community composition.

The paper develops M2AE, a multi-task multi-view model to impute blood SCFA levels using gut metagenomic data, dietary features, and host characteristics, showing improved performance over existing methods.

This study shows that infant gut microbiota at 1 month are most responsive to dietary changes, while 18-month-olds show resilience, with formula affecting fewer metabolic pathways than breast milk.

The paper isolates and genomes three Clostridium leptum-related bacteria from fecal samples, identifies a new species, and assesses their dietary response in a clinical trial context.

This study identifies cachexia-associated microbial metabolites using computational modeling and metabolomic analyses in a murine cancer model.

This study compares the oral, gut, and hair microbiomes of wild and captive lemurs, finding that the oral microbiome is more resilient to environmental changes than the hair microbiome.

The study tests the effect of microbiota complexity and age on gut microbiota stability in SCID piglets, finding age affects composition but not genotype, and the 7-strain consortium is most stable.

This study compares the gut microbiomes of Ju/hoansi hunter-gatherers, agropastoralists, and Western urban populations, finding higher diversity and health-associated pathways in the former.

The paper identifies key microbial interactions and metabolic pathways that confer resistance to C. difficile invasion using synthetic and clinical communities.

This study analyzes the gut microbiome of state-threatened gopher tortoises in Florida to assess health and ecological implications.

The paper investigates how maternal immune dysregulation and dysbiosis affect offspring gut immune homeostasis and T1D development in NOD mice.

This study shows that morphine self-administration in rodents alters gut microbiota and brain microstructure, with neuroinflammation linking gut and brain changes.

The paper refines enterotypes in global fecal metagenomes using fuzzy clustering and introduces an Enterotype Dysbiosis Score to assess disease associations.

This study identifies causal relationships between gut microbiome, metabolic dysfunction-associated fatty liver disease (MAFLD), and blood metabolites using Mendelian randomization.

The paper compares microbiome composition and function across rheumatic diseases to identify microbial signatures predicting methotrexate response in RA and PsA.

The paper develops an in vitro model to study gut microbiota-dependent bile acid changes induced by lincosamides, showing consistent results with an in vivo study.

This paper develops a fast targeted metabolomics method to analyze indole derivatives in ME/CFS gut microbiome samples, revealing metabolic differences that may serve as biomarkers.

This study shows that gut microbiome changes affect lurasidone bioavailability in rats, with prebiotics increasing it 4.3-fold and antibiotics reducing it in 80% of animals.

The paper evaluates long-term effects of antibiotics and human-targeted medications on the gut microbiome using electronic health records and metagenomics data.

This study investigates the relationship between fecal microbiome and serum uremic toxins in hemodialysis patients, finding that dietary protein-to-fiber ratio, not microbiome composition, is significantly associated with toxin levels.

This study finds a significant association between changes in gut microbiome composition and reduction in ADHD symptoms in children following a few-foods diet.

This study uses a genetic hypogonadal mouse model to show that the HPG axis influences gut microbiome maturation during puberty, with some sex differences independent of the HPG axis and age also playing a role.

This paper introduces CoPR, a framework for analyzing microbial community activity through collective pattern recognition across multiple datasets, revealing insights into individuality and conformity in temporal abundance profiles.

This study profiles the gut microbiome of Ugandan COVID-19 patients and identifies microbial associations with disease severity using machine learning.