Salmonella and Campylobacter epidemiology

Ancient genomic insights into Salmonella enterica Paratyphi C in Central Mexico

This study identifies ancient S. enterica Paratyphi C DNA in 19th-century Mexico, linking it to European strains and showing its persistence in urban settings.

The Gfr uptake system provides a context-dependent fitness advantage to Salmonella Typhimurium SL1344 during the initial gut colonization phase

The paper shows that the gfr operon in Salmonella Typhimurium provides a fitness advantage during gut colonization by utilizing dietary Amadori compounds like fructoselysine.

Genomic factors contributing to the resilience of Salmonella enterica on ready-to-eat muskmelon

This study identifies genes in Salmonella enterica serovars that influence their survival on muskmelons, revealing shared and serovar-specific genetic factors.

The resilience of Salmonella to bile stress is impaired due to the reduced efflux pump activity mediated by the antioxidant enzyme YqhD

This study shows that YqhD in Salmonella reduces reactive oxygen species and efflux pump activity, impairing bile resistance, and that its mutation increases survival in bile stress conditions.

Recombinant Lactococcus lactis-based multivalent vaccine targeting Campylobacter jejuni colonisation and modulating cecal microbiota in poultry

This study develops a multivalent mucosal vaccine using Lactococcus lactis expressing C. jejuni antigens to reduce colonization and modulate gut microbiota in poultry.

Evolutionary history and recurrent host adaptation in ancient Salmonella enterica

This study reconstructs the evolutionary history of ancient Salmonella enterica using 53 new genomes, revealing host adaptation events and convergent evolution in pathogenic lineages.

American black bear (Ursus americanus) as a potential host for Campylobacter jejuni

This study identifies C. jejuni strains in American black bears, showing genetic diversity and potential host-specific adaptations.

Commensal Yeast Promotes Salmonella Typhimurium Virulence

This study shows that the commensal fungus Candida albicans enhances Salmonella Typhimurium virulence by promoting arginine production, which in turn boosts Salmonella's ability to invade host cells and dampens the host's inflammatory response.

Virotrap Reveals Salmonella SopB as A Ubiquitinated Cargo for Host ESCRT-0

This study identifies SopB-associated host proteins using Virotrap, revealing SopB's interaction with ESCRT-0 and its role in Salmonella's manipulation of host endosomal trafficking.

Exploring Transcriptomic Changes in Antibiotic-Resistant Salmonella Heidelberg Modulated by Commensal Escherichia coli in Vitro

This study shows that commensal E. coli 47-1826 reduces antibiotic-resistant S. Heidelberg 18-9079 fitness, virulence, and AMR by modulating its transcriptome in vitro.

Risk factors for fluoroquinolone- and macrolide-resistance among swine Campylobacter coli using multi-layered chain graphs

The paper uses chain graphs to identify risk factors for fluoroquinolone- and macrolide-resistance in Campylobacter coli from swine farms, finding genotype and host exposures explain significant variance in MICs.

Genomic diversity of non-typhoidal Salmonella found in patients suffering from gastroenteritis in Norfolk, UK

This study analyzes genomic diversity in Salmonella isolates from gastroenteritis patients, revealing microevolution and structural variation, and highlights the limitations of single-colony sequencing.

High prevalence of multi-drug resistant bacteria in faecal samples from UK passerine birds

This study finds that 75% of UK passerine birds carry multi-drug resistant bacteria, with young birds and certain species being particularly high carriers.

Pangenome and comparative genomics analysis reveal patterns of quorum sensing and antimicrobial resistance in Salmonella Lineages from African Food Chains

This study analyzes Salmonella genomes from African food chains to identify patterns of antimicrobial resistance and quorum sensing, revealing lineage-specific genes and geographic diversity.

The viable but non-culturable (VBNC) state of Campylobacter jejuni lacks propagation ability in the mouse intestinal tract

This study shows that Campylobacter jejuni in the VBNC state cannot colonize the mouse intestinal tract, suggesting it may not pose a food poisoning risk.

PgtE protease enables virulent Salmonella to evade C3-mediated serum and neutrophil killing

This study shows that PgtE protease in virulent Salmonella Typhimurium helps evade complement-mediated killing by cleaving C3, enabling systemic spread.

Genomic Insights into the Diversity, Antimicrobial Resistance, and Zoonotic Potential of Campylobacter fetus Across Diverse Hosts and Geographies

This study analyzes 114 C. fetus genomes to explore genetic diversity, antimicrobial resistance, and zoonotic potential across hosts and geographies.

Slow-growing Salmonella enterica Typhi mis-identified as Salmonella Gallinarum in Ibadan, Nigeria

This study identifies slow-growing Salmonella Typhi misidentified as S. Gallinarum in Nigeria, showing the need for extended motility testing and molecular confirmation.

Immune Responses to Salmonella Typhi Antigens among Typhoid Recovered Individuals in an Endemic Region

The paper evaluates humoral and cellular immune responses to Salmonella Typhi antigens in typhoid-recovered individuals, finding elevated IgA and TEMRA cells, and comparable IgG and memory B cells between groups.

Genomic analysis identifies Campylobacter concisus genomospecies 2 as a novel species and proposes the name Campylobacter oralis

Acanthamoeba castellanii as a model for unveiling Campylobacter jejuni host-pathogen dynamics

This study investigates how Campylobacter jejuni interacts with Acanthamoeba castellanii, revealing metabolic and genetic changes in the amoeba that may aid bacterial survival.

Genomic Analysis of Salmonella enterica from cattle, beef and humans in the Greater Tamale Metropolis of Ghana

This study analyzes Salmonella enterica isolates from cattle, beef, and humans in Ghana, identifying novel sequence types and antimicrobial resistance genes, and showing close genetic relatedness between human and bovine isolates.

Elucidating the perception, awareness and biosecurity practices among the live poultry/poultry-meat sellers to mitigate the risk of zoonotic salmonellosis

This study assesses knowledge, attitudes, and biosecurity practices of poultry sellers in Bangladesh to reduce zoonotic salmonellosis risk, finding that education and training significantly influence their practices.

Salmonella hijacks a host glucose transporter for intravacuolar proliferation

This study identifies how Salmonella uses GLUT1 to access glucose for intracellular growth, revealing a three-step mechanism involving MAPK activation, GLUT1 membrane targeting, and ubiquitination.

Single-cell tracking of genetically minimized Salmonella reveals mechanisms of effector gene cooperation.

This study uses genome minimization and single-cell mass cytometry to identify effector genes in Salmonella that drive pathogen dissemination between immune cells.

The TyphiNET data visualisation dashboard: Unlocking Salmonella Typhi genomics data to support public health

The paper introduces TyphiNET, a dashboard for exploring Typhi genomics data to support public health decisions on antimicrobial resistance and vaccine implementation.

Maltose attenuates the virulence of Salmonella Typhimurium by impairing its entry into epithelial cells

This study shows maltose reduces Salmonella Typhimurium's ability to infect epithelial cells by decreasing adhesion through type 1 fimbriae.

Evasion of serum antibodies and complement by Salmonella Typhi and Paratyphi A

This study compares how Salmonella Typhi and Paratyphi A evade serum antibodies and complement compared to S. Typhimurium, identifying differences in O-antigen and Vi capsule production.

Case study: Genomic characteristics of the gut microbiome, Campylobacter and Salmonella genotypes in three cases of gastroenteritis co-infections

This study examines the genomic characteristics and microbiome composition in three cases of Campylobacter and Salmonella co-infections, revealing distinct pathogen strains and microbiome profiles.

STRAIN-SPECIFIC VIRULENCE SIGNATURES OF CAMPYLOBACTER JEJUNI ASSOCIATED WITH WATERY VERSUS BLOODY DIARRHEA IN NEONATAL PIGLET MODEL

This study compares C. jejuni strains causing watery or bloody diarrhea in piglets, finding that bloody strains exhibit greater virulence traits like cell invasion and barrier disruption.