Efficient Permutation-based Genome-wide Association Studies for Normal and Skewed Phenotypic Distributions
Maura John, Markus Johannes Ankenbrand, Carolin Artmann, Jan A. Freudenthal, Arthur Korte, Dominik G. Grimm
The paper introduces permGWAS, a permutation-based GWAS method that improves significance thresholds for skewed phenotypes and reduces false discovery rates compared to Bonferroni correction.
Bioinformatics · Aug 24, 2022Peer-reviewedBioinformatics