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The paper develops an integrative imaging pipeline combining micro-CT and scanning electron microscopy with histology to enhance lung tissue analysis by adding 3D context and ultrastructural details.

This study examines pulmonary arterial remodeling in COVID-19 patients through histopathological analysis of autopsy lung samples, finding thickened vascular walls and associations with disease duration and vascular changes.

This paper develops two digital droplet PCR assays to detect and differentiate three barley pathogens from seeds, achieving sensitive and specific detection at low concentrations.

This paper presents a framework for integrating deep-learning models into the laboratory information system using open-source tools and HL7 standards to support clinical adoption in digital pathology.

Barcoded murine polyomavirus tracked in mouse urine shows many barcodes shed at low levels throughout infection, a few dominating high-level shedding late, and kidney implicated as a primary source.

This study identifies a contracted anterior-posterior organizational axis of cortical thickness in early-onset schizophrenia using structural MRI data.

This study uses computational modeling to show that polyglutamine expansion in the androgen receptor's N-terminal domain causes dynamic misfolding, altering interdomain interactions and potentially leading to SBMA pathology.

This paper introduces an optimized silver nitrate staining method for visualizing the osteocyte lacuno-canalicular system, showing improved staining consistency and LCS detection across species.

This paper introduces a novel genetic mouse model of aortic dissection showing immune cell infiltration and altered ECM dynamics.

This study shows that smooth-muscle calcineurin, independent of its phosphatase activity, drives a gene expression program that causes hypertension.

This study examines how RAGE signaling and Type 2 Diabetes affect cortical bone mechanics, structure, and material properties in mice, showing sex-specific improvements with RAGE ablation.

This study identifies two distinct cell proliferation populations during liver regeneration in mice with acute liver injury using single-cell RNA-seq.

This study identifies TRPV4 as a cellular stiffness sensor linking matrix stiffness and atherosclerosis using human tissues and a mouse model.

Across nine Kenyan counties, Stomoxys flies fed on 15 vertebrate hosts, carried Anaplasma, Theileria/Babesia and Trypanosoma DNA, and transmitted T. vivax, T. evansi and Theileria mutans to mice.

This study uses PET imaging to show a strong positive correlation between mGluR5 and synaptic density in early AD patients and cognitively normal individuals, suggesting mGluR5 may mediate early synaptic loss in AD.

This study shows that bone pain in Fibrous dysplasia is intrinsic and not caused by abnormal sensory nerve sprouting or neuroma formation.

This study shows that silencing KRIT1 in endothelial cells under disturbed flow restores KLF2 and KLF4 expression, mimicking the transcriptomic profile of cells under laminar flow.

This paper harmonizes TUNEL with multiplexed immunofluorescence to improve spatial contextualization of cell death in tissues.

This study shows that KUS121 reduces atherosclerosis by maintaining ATP levels and reducing ER stress in endothelial cells.