Q. Chen

This paper shows that HCFC1 and HCFC1R1 deficiencies block HSV-1 infection by inhibiting nuclear translocation of HCFC1 and VP16, offering potential new therapeutic targets.

This study shows filamentous bacteriophage delays wound healing in Pseudomonas aeruginosa infections by inhibiting keratinocyte migration, supported by a patient cohort study.

The paper investigates how carbon-based additives and ventilation rates affect nitrogen loss and microbial communities in chicken manure composting, finding that woody peat reduces nitrogen loss more effectively than other additives.

This study shows infrared heater warming reduces dew formation by 41.6%-91.1% and shortens its duration by 32.1 days in alpine grasslands.

This study investigates how fungal communities in vineyards influence wine aroma and quality by analyzing microbial distribution patterns across six Australian winegrowing regions.

This study shows that Cep57 and Cep57l1 recruit the Cep63-Cep152 complex to mother centrioles, enabling centriole duplication.

This study examines how CO2 responses of photosynthesis in Hippophae rhamnoides leaves vary under different soil moisture conditions using multiple models.

This study examines the overwintering behavior and cold hardiness of the purple stem borer in its newly colonized northern range, identifying its survival strategies and potential distribution limits.

This study introduces a new teaching method for medical statistics called PDTR, which improves student performance and reduces class hours compared to traditional methods.

This paper explores data quality issues in biological databases, focusing on duplication and other problems, and highlights the role of biocuration in addressing them.

This study shows N-acetyl cysteine (NAC) reduces silver-induced reactive oxygen species (ROS) in human cells without affecting silver's antimicrobial activity.

This paper proposes a strategy to select crop varieties based on yield factors and meteorological predictions, showing 70% and 50% success rates in two pilot regions for soybean variety selection.

This study identifies immune-related genes under positive selection in schizothoracine fish, linking their adaptive evolution to speciation and local adaptation on the Qinghai-Tibetan Plateau.

This study identifies G-CSF as a metabolic niche factor that replenishes Pax7Hi muscle stem cells in aged mice through exercise-induced mechanisms.

This paper proposes a runaway mutation model explaining how mutator mutations can lead to escalating mutation rates in both germline and somatic tissues, affecting evolutionary strategies across species.

This paper develops a syngeneic mouse model of tobacco-associated HNSCC that shows high response rates to anti-CTLA-4 therapy.

This paper develops a CRISPR-based colorimetric gene detection platform using AuNPs that enables naked-eye detection of DNA and RNA targets with high sensitivity and universality.

This study identifies Pkd2p, a TRP channel in fission yeast, as a regulator of cytokinesis by modulating osmotic homeostasis and cell separation.

This paper develops a laser-based system to record subcellular neuron activities with high sensitivity, showing that ultrasound can modulate neuron laser emissions.

The paper examines codon substitution rates across species and finds that evolutionary rates are strongly negatively correlated with amino acid distance under predominant negative selection.

The paper shows that siRNA with a 5-nucleotide motif suppresses DNA-mediated IFN and cytokine signaling by inhibiting IFI16-DNA binding.

This study identifies two regions on MiD51 that bind Drp1 and shows that MiD51 dimerization via a disulfide bond is required for Drp1 recruitment, revealing a multi-faceted regulatory mechanism for mitochondrial fission.

This study identifies and characterizes a novel pic gene cluster in Alcaligenes faecalis JQ135 responsible for complete picolinic acid degradation into the tricarboxylic acid cycle.

The paper shows that positive selection drives amino acid substitutions with large chemical property changes, while negative selection favors smaller changes, suggesting distinct evolutionary mechanisms.

The paper introduces an M-value to quantify mitochondria-lysosome contact and mitophagy using structured illumination microscopy, finding distinct M-value ranges for these processes.

The paper shows that mother centrioles are not required for deuterosome formation and function during basal body amplification in multiciliate cells.

This paper develops a CRISPR/Cas9-edited CHO cell line deficient in MGAT1 to produce HIV-1 gp120 with early glycosylation intermediates, enhancing binding to glycan-dependent broadly neutralizing antibodies.

The paper develops an iridium(III) dye for tracking mitochondrial dynamics under structured illumination microscopy, revealing new insights into mitochondria-lysosome interactions.

This study shows that Elongator regulates SHORT ROOT transcription in Arabidopsis roots, essential for stem cell maintenance and radial patterning.

This study identifies a de novo BK channel mutation causing epilepsy by enhancing voltage-dependent activation, while not affecting calcium sensitivity.