R. Singh

The paper reports high-resolution structures of actin isoforms with native PTMs, revealing isoform-specific conformations and their functional implications.

This study identifies an Mn2+-dependent small RNA-mediated regulation of T6SS in A. baumannii, revealing how Mn2+ influences sRNA binding to repress T6SS.

The paper shows that mTORC2 activation during fasting promotes mitochondrial fission and respiratory function through NDRG1 phosphorylation and interaction with Cdc42.

This paper introduces a mesoscopic oblique plane microscope capable of imaging freely moving organisms at cellular resolution, demonstrating its use on sea anemones.

The paper identifies subcellular localization of effector proteins from the maize pathogen Phyllachora maydis using fluorescent tagging and microscopy.

This study compares transcriptional responses of AB-resistant and susceptible chickpea genotypes to A. rabiei infection, identifying key pathways and hub genes involved in resistance.

The paper identifies molecular differences in adventitious rooting competence between two poplar genotypes and shows that MYC2 expression levels influence rooting ability.

This study examines gene flow and recombination between biocontrol strains and native A. flavus populations, showing increased gene flow from lineage IB to IC after biocontrol application.

This study evaluates a highly thermotolerant SARS-CoV-2 vaccine in mice, showing it elicits neutralizing antibodies against Delta and Omicron variants.

This study investigates the range extension of the Himalayan Vagrant butterfly, finding no range shift or vagrancy, and highlights issues with citizen science data accuracy.

This study investigates the biomaterial potential of recombinant Streptococcal collagen-like (rScl1) protein, showing its non-cytotoxicity, cell-adhesion support, and efficacy in diabetic wound closure with increased type III collagen.

The paper identifies PTMs on β-MHC in human hearts and shows their changes in failing hearts, suggesting acetylation levels are influenced by PTM location rather than disease type.

This study identifies HopG1 as a T3SE that induces necrotic cell death and shows that AtNHR2B inhibits its virulence functions in Arabidopsis.

This study investigates how Lewy Bodies (LBs) and Syn-aggresomes interact in neurons, showing LBs overgrow and cause proteostatic issues through lamina injuries and dynein-force imbalances.

This study shows Chi3l1 modulates glioma stem cell states by altering transcription factor activity and cell state transitions, and demonstrates anti-Chi3l1 antibody treatment inhibits glioblastoma growth.

The paper studies actinobacteria from marine sponges and associated environments, identifying new species and reporting predatory behavior and antibacterial activity.

This study characterizes Rv0792c, a GntR homolog from M. tuberculosis, identifies small molecule inhibitors, and reveals its role in stress adaptation and virulence.

This paper develops an immunocompetent ER+ breast cancer mouse model with spontaneous bone metastasis and antiestrogen responsiveness, showing treatment efficacy with tamoxifen and fulvestrant.

The Ascochyta rabiei effector ArPEC25 enters the host nucleus and targets the transcription factor CaβLIM1a to manipulate phenylpropanoid pathway for negative modulation of chickpea lignin biosynthesis.

This study shows that the transcriptional response to oxidative stress in Drosophila cells occurs independently of stress granule formation.

This study shows that PLP supplementation increases the expression and activity of a PLP-dependent model protein in E. coli, suggesting possible transport mechanisms for PLP.

This study uses csRNA-seq to identify transcriptional changes and regulatory elements during phase transition in Coccidioides immitis, revealing a WOPR homologue involved in pathogenicity.

This study evaluates a multivalent Ad-vectored vaccine delivered via respiratory mucosal route, showing robust protection against SARS-CoV-2 and variants in mice.

The paper introduces a single BsaHI digestion method to detect and differentiate avirulent NDV strains from virulent ones using RT-PCR and sequence analysis.

This study identifies Snail's role in maintaining stem/progenitor state in skin epithelial cells and carcinomas via Mindin-mediated autocrine signaling.

This study identifies a Serpin27A-dependent Toll signaling pathway in Drosophila that mediates cancer resistance through NF-κB-mediated tumor cell death.

The paper evaluates plasma protein purification protocols for HIV-1 infected human plasma, finding that the Aurum serum mini kit provides better resolution of low-abundance proteins in 2-D gel electrophoresis.

The paper identifies a first-in-class inhibitor, BRD0639, that targets the PRMT5-PBM interaction, disrupting SAP binding and reducing substrate methylation in cancer cells.

This paper demonstrates a drug-free strategy using magnetic nanoparticles formed by bacteria to combat infections, showing significant bacterial reduction with an alternating magnetic field.

This study shows how the MDA5 variant M854K impairs ATP-dependent RNA discrimination, leading to autoimmune disease by allowing misrecognition of endogenous RNAs.