S. Wu

This study shows that ITGB4 in airway epithelial cells reduces CCL17 production, thereby suppressing Th2 responses and allergic inflammation in asthma.

B cells integrate innate TLR and adaptive CD40 signals to induce BATF3 transcription factor for production of IL-27, which together with INFg optimizes antibody responses.

This paper evaluates population density maps using census data from Bioko Island, finding that LandScan best captures urban areas, HRSL performs well in rural areas, and WorldPop is less accurate overall.

This paper describes a rapid method using LAMP and Nanopore Flongle for detecting SARS-CoV-2 and other respiratory viruses in under two hours.

This study shows Mg2+ promotes bone regeneration initially by modulating macrophage activity but later inhibits bone formation through NF-κB activation and reduced hydroxyapatite precipitation.

This study shows that intestinal VDR protects against dysbiosis and tumorigenesis by modulating the JAK/STAT pathway through microbiome interactions.

The paper introduces a deep learning method to predict virus hosts using DNA sequences, applied to 2019-nCoV to identify potential hosts like bats and minks.

This study shows that extrachromosomal DNA amplification of oncogenes is common in human cancers and is associated with worse patient outcomes.

This study characterizes carbapenem-resistant Klebsiella pneumoniae isolates, identifying ST11 as the main type and blaKPC-2 as the dominant carbapenemase gene.

This study identifies LncRNA MIR4435-2HG as a mediator of cisplatin resistance in HCT116 cells via the Nrf2/HO-1 pathway.

This study shows TRIM21 and PHLDA3 regulate cross-talk between PI3K/AKT signaling and PPP metabolism, with implications for cancer therapy.

This study shows that exposure to environmental-level pesticides with antibiotics increases antibiotic resistance in E. coli through synergistic effects and genetic diversification.

This paper identifies the role of TYLCV V2 protein in facilitating the nuclear export of V1 protein and viral systemic infection through host exportin and V1-V2 interaction.

The paper analyzes the miRNA-mRNA network regulated by LMP1 in NPC using microarray data to identify differentially expressed miRNAs and genes and construct interaction models.

The paper develops a lipid-free medium with insulin, transferrin, and selenium to study de novo fatty acid synthesis in melanoma cells and shows it activates relevant gene transcription.

The paper presents cryo-EM structures of SNF2h-nucleosome complexes with ADP-BeFx, revealing conformational states that suggest allosteric control through the nucleosome.

This study investigates the structure-activity relationship of cinnamodial analogues against Aedes aegypti, identifying key functional groups for larvicidal, adulticidal, and antifeedant activity.

This study shows how varying actin shell thickness in reconstituted systems controls membrane shape changes under volume reduction, revealing a transition between buckling and wrinkling.

This study identifies DEK5 as a homolog of bacterial TamB required for chloroplast envelope biogenesis and metabolite transport in maize.

This study shows that gut segments, not diet, are the main factor shaping the intestinal microbiome in grass carp, with diet having a smaller impact in distal gut regions.

The paper demonstrates that SHR and stele-derived small peptides coordinate to rebuild functional Casparian strips in non-endodermal cells through two parallel signaling systems.

This study predicts the evolutionary pathway of norovirus escaping antibodies using a biophysical fitness model, validated by experimental evolution in bulk culture and microfluidics.